Facile Green Synthesis of NiO/NiCo₂O₄ Nanocomposite as an Efficient Electrochemical Platform for Determination of Dopamine

Abstract

The synthesis of NiO/NiCo2O4 nanoparticles by an eco‐friendly, fast, simple and cost‐effective approach employing Urtica extract is reported in this study. The NiO/NiCo2O4 nanocomposite were characterized using VSM, FTIR, XRD, and SEM techniques. Moreover, to construct a modified carbon paste electrode, NiO/NiCo2O4 were employed and this sensor was used for dopamine (DA) detection. Using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques, the electrochemical behavior of dopamine at the NiO/NiCo2O4/CPE was investigated. Analysis of dopamine, with a limit of detection (LOD) equal to 0.04 μM, in the concentration range of 0.1–100.0 μM, was facilitated by NiO/NiCo2O4/CPE. Moreover, the satisfactory selectivity for DA determination in the presence of uric acid (UA) and ascorbic acid (AA), was obtained. The suggested new sensor displayed a good reproducibility, sensitivity, and stability for determination of DA in drug and biological samples.

Au/In2O3 Nanocubes Based Label‐free Aptasensor for Ultrasensitive and Rapid Recognition of Cardiac Troponin I

“…Figure S4C presented that both peak currents in redox enhanced with the increase of the scan rate. The values of the peak currents followed a linear dependence with the root of the scan rate [47], verifying that the detection process was dominated by a diffusion‐controlled reaction to closely associate with the target concentration (Figure S4D). In this case, the as‐prepared biosensor is capable of the quantitative detection of cTnI.…”

A new electrochemical DNA biosensor for determination of anti-cancer drug chlorambucil based on a polypyrrole/flower-like platinum/NiCo2O4/pencil graphite electrode

“…It has greater electrochemical potential and electronic conductivity when compared with Ni and Co oxides alone. [36][37][38] In addition, metal oxide semiconductor doping can create an excess or deciency of the count of electrons that can modulate the semiconductor conductivity. The noble metals such as Au, Ag, Pd and Pt can be used for doping the NiCo 2 O 4 nanostructures to enhance active surface area and promote electronic properties, resulting in greater sensor response compared to NiCo 2 O 4 .…”

Actualities in immunological markers and electrochemical sensors for determination of dopamine and its metabolites in psychotic disorders (Review)

“…The performance characteristics of other recently reported electrochemical sensors for DA detection are summarized in Table I (73)(74)(75)(76)(77)(78)(79)(80)(81)(82)(83)(84)(85)(86)(87)(88)(89)(90).…”