Facile one-step electrochemical fabrication of a non-enzymatic glucose-selective glassy carbon electrode modified with copper nanoparticles and graphene

Abstract

We have developed a non-enzymatic glucose sensor by using a composite prepared from copper nanoparticles (CuNPs) and graphene which can be prepared by simple 1-step electrochemical reduction using graphene oxide (GO) and copper ion as the starting materials. The GO is electrochemically reduced to graphene at a voltage of −1.5 V, and this is accompanied by the simultaneous formation of CuNPs on the surface of the graphene. This novel nanocomposite combines the advantages of graphene and of CuNPs and displays good electrocatalytic activity toward glucose in alkaline media. The performance of the respective glucose electrode was evaluated by amperometric experiments and revealed a fast response (<2 s), a low detection limit (200 nM), and high sensitivity (607 μA mM −1 ). The sensor also exhibits good reproducibility and very good specificity for glucose over ascorbic acid, dopamine, uric acid, fructose, lactose and sucrose.

Cu(III)-independent oxidation and sensing of glucose on multi-layer stacked copper nanoparticles

“…For enzyme-free glucose sensing, non-noble metals such as Cu and Ni have been widely studied as the anodes of glucose oxidation in alkaline media [2]. Many research efforts are focused on preparing Cu nanoparticles (NPs) or nanocomposites, such as Cu NPs/GR [3], Cu-CuO NWs [4], CuNWs [5], Cu foam [6], CuO/rGO [7], Cu/porous silicon [8], CuO nanoleaf/ZnO nanorods [9], and Cu 2 O/NiO x /GO [10].…”

Phosphomolybdic acid functionalized graphene loading copper nanoparticles modified electrodes for non-enzymatic electrochemical sensing of glucose

“…3.0 × 10 -2 µM (S/N=3), which was lower than that of CuNPs-GR/GCE [42,43]. The reason was that the introduction of PMo 12 , which was efficient for the uniform growth of CuNPs and electron transport.…”

Electrochemical determination of total reducing sugars from bioethanol production using glassy carbon electrode modified with graphene oxide containing copper nanoparticles

“…2(C). The bands associated at $1328, $1600, 2677 and 2922 cm À1 correspond to D (defect band due to intervalley scattering), G (graphene band), 2D and D + G bands, respectively [31][32][33]. After applying the potential of À0.7 V, it was observed that the intensity of the D and G bands is not reversed, once graphene oxide is not reduced to graphene.…”