Facile synthesis of a new Cu(ii) complex with an unsymmetrical ligand and its use as an O₃ donor metalloligand in the synthesis of Cu(ii)–Mn(ii) complexes: structures, magnetic properties, and catalytic oxidase activities

Abstract

Four new heterometallic Cu(ii)–Mn(ii) complexes have been synthesised by using a Cu(ii) complex of an unsymmetrical Schiff base as O3 donor ligand; one of which is catalytically active towards catecholase and phenoxazinone synthase activities.

Modulation of Nuclearity in CuII−MnII Complexes of a N2O2 Donor Ligand Depending upon Carboxylate Anions: Structures, Magnetic Properties and Catalytic Oxidase Activities

“…The catecholase and phenoxazinone synthase‐likeactivity of the complexes ( 1–3 ) in details were investigated UV‐vis spectrophotometrically by monitoring the catalytic oxidation of 3,5‐di‐tert‐butylcatechol (3,5‐DTBC), and o ‐aminophenol (OAPH), respectively at room temperature in DMF‐acetonitrile solution, as reported previously (Scheme 2). [11b] …”

“…Initial rate method is applied to determine the reaction kinetics of the oxidation of 3,5‐DTBC, and OAPH by measuring the growth of the quinone, and APX band at 401, and 418 nm, respectively as a function of time (time scan) [11b] . The concentration of the complexes ( 1 – 3 ), and the different concentrations of 3,5‐DTBC/OAPH used during time scan for each case are given in Tables S8 and S9.…”

“…The polydentate coligand carboxylates deserve special mention in this regard as they have been found very useful in modulating the phenoxido bridging angles between the metal centres in a wide range to verify experimentally the ferro‐ to antiferromagnetic crossover angle [16] . The hetero‐metallic complexes with carboxylate coligands are also found to be catalytically very efficient [11b] . It is worthy to note that all these metalloligands, have been synthesized by reacting a diamine with salicylaldehyde or its derivatives; napthaldehyde derivatives have never been used for this purpose until recently when we used copper(II) chelate of o ‐hydroxynapthaldehyde and 1,3‐propanediamine as “metalloligands” to prepare hetero‐metallic Cu II 2 Cd II complexes [17] …”

Ligand directed synthesis of a unprecedented tetragonalbipyramidal copper (II) complex and its antibacterial activity and catalytic role in oxidative dimerisation of 2‐aminophenol

“…[ 8–11 ] It pursuit of deep understanding of different biological oxidation processes in nature, synthetic coordination chemists have been stepped forward to tune electronic and geometric factors of the ligands in engineering bio‐inspired coordination driven compounds. [ 12–15 ] It is well documented that the bio‐inspired synthetic analogues also serve as magic catalysts in several catalytic oxidation reactions of laboratory and industrial significance. [ 14–16 ] Among the different oxidase enzymes, phenoxazinone synthase has drawn special attention [ 14,15 ] as the oxidized product, aminophenoxazinone acts as an antineoplastic agent named actinomycin D (questiomycin A) which is usually recommended in the treatment of certain types of cancer.…”

“…[ 12–15 ] It is well documented that the bio‐inspired synthetic analogues also serve as magic catalysts in several catalytic oxidation reactions of laboratory and industrial significance. [ 14–16 ] Among the different oxidase enzymes, phenoxazinone synthase has drawn special attention [ 14,15 ] as the oxidized product, aminophenoxazinone acts as an antineoplastic agent named actinomycin D (questiomycin A) which is usually recommended in the treatment of certain types of cancer. [ 17–20 ] Furthermore, 2‐aminophenoxazin‐3‐one and 3‐aminophenoxazin‐2‐one compounds show potential antimicrobial, antiviral, and antitumor activities against different pathogens.…”