Factores asociados a muerte en niños con COVID-19 en México

Rivas-Ruíz, Rodolfo; Roy-García, Ivonne; Ureña-Wong, Kingston; Aguilar-Ituarte, Felipe; Anda, Gilberto Felipe Vázquez-De; Gutiérrez‐Castrellón, Pedro; Mancilla-Ramı́rez, Javier; Moreno-Espinosa, Sarbelio

doi:10.24875/gmm.20000478

Cited by 9 publications

(12 citation statements)

References 22 publications

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“…The three prognostic models presented in this work analyze the effect that risk variables have in different scenarios, particularly in patients in ICU; the analysis of Ñamendys Silva is consistent (12), who analyzed the decision made by the health authorities in Mexico during the second wave of infections, in December 2020, when the number of beds with a ventilator increased by 4.7 times (from 2,446 to 11,634) in hospital areas not equipped with intensive care, consequently, mortality was 12% higher, probably explained by human resources and the equipment had a lower quality of care. A recently published analysis in the pediatric population demonstrated the relationship among age, the clinical presentation with intubation, and the need for intubation as the variables associated with mortality (27). Some limitations of this study include the following: (a) As each hospital center feeds the database and the results are issued as cases are added, reports on the outcomes are subject to the data being updated.…”

Section: Discussionmentioning

confidence: 99%

Coronavirus Disease-2019 Survival in Mexico: A Cohort Study on the Interaction of the Associated Factors

Márquez-González

Méndez-Gálvan

Reyes‐López

et al. 2021

Front. Public Health

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The pandemic caused by the new coronavirus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is currently affecting more than 200 countries. The most lethal clinical presentation is respiratory insufficiency, requiring attention in intensive care units (ICU). The most susceptible people are over 60 years old with comorbidities. The health systems organization may represent a transcendental role in survival.Objective: To analyze the correlation of sociodemographic factors, comorbidities and health system organization variables with survival in cases infected by SARS-CoV-2 during the first 7 months of the pandemic in Mexico.Methods: The cohort study was performed in a health system public basis from March 1st to September 30th, 2020. The included subjects were positive for the SARS-CoV-2 test, and the target variable was mortality in 60 days. The risk variables studied were: age, sex, geographic distribution, comorbidities, health system, hospitalization, and access to ICU. Bivariate statistics (X2-test), calculation of fatality rates, survival analyses and adjustment of confusing variables with Cox proportional-hazards were performed.Results: A total of 753,090 subjects were analyzed, of which the 52% were men. There were 78,492 deaths (10.3% of general fatality and 43% inpatient). The variables associated with a higher risk of hospital mortality were age (from 60 years onwards), care in public sectors, geographic areas with higher numbers of infection and endotracheal intubation without management in the ICU.Conclusions: The variables associated with a lower survival in cases affected by SARS-CoV-2 were age, comorbidities, and respiratory insufficiency (with endotracheal intubation without care in the ICU). Additionally, an interaction was observed between the geographic location and health sector where they were treated.

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Section: Discussionmentioning

confidence: 99%

Coronavirus Disease-2019 Survival in Mexico: A Cohort Study on the Interaction of the Associated Factors

Márquez-González

Méndez-Gálvan

Reyes‐López

et al. 2021

Front. Public Health

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“…Obesity is one of the most controversial risk factors. In a study of mortality of children with COVID-19 in Mexico, obesity was found not to be an associated risk factor 7 . In contrast, in a group of children hospitalized at a children's hospital in New York, 50% of which were Hispanic, obesity was the main comorbidity (22%) and was significantly associated with mechanical ventilation in children > 2 years of age (6 of 9 [67%] vs. 5 of 25 [20%]) 18 .…”

Section: Discussionmentioning

confidence: 93%

“…Pneumonia is a well-known risk factor for children with COVID-19 for both death and admission to intensive care 7 . One of the main risk factors for a bad prognosis is lung damage.…”

Section: Discussionmentioning

confidence: 99%

“…Pneumonia is the leading risk factor for admission to intensive care unit (ICU), mechanical ventilation, and death in children infected with SARS-CoV-2 7 . While it was thought that children were protected against this virus, recent reports show that the pediatric population is not excluded from COVID-19 and its complications, possibly due to their immune system immaturity 8 .…”

Section: Introductionmentioning

confidence: 99%

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Risk factors associated with SARS-CoV-2 pneumonia in the pediatric population

Moreno-Noguez¹,

Rivas-Ruíz²,

Roy-García³

et al. 2021

BMHIM

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Background: Currently, there are a few studies on the clinical characteristics of the pediatric population with This study aimed to analyze data associated with the development of pneumonia in children and adolescents with SARS-CoV-2 infection throughout Mexico. Methods: We conducted a secondary analysis of the database of the Dirección General de Epidemiología of the Mexican Government. We included children under the age of 19 who were confirmed with SARS-CoV-2 infection by reverse transcription-polymerase chain reaction (RT-PCR) test. The dependent variable was the diagnosis of pneumonia. Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated. Multiple logistic regression models were performed to adjust factors associated with pneumonia. Results: A total of 1443 children with a COVID-19 diagnosis were included. The median age of the participants was 12 years (interquartile range 25, 75: 5, 16). Pneumonia occurred in 141 children (9.8%). The main risk factors were age < 3 years (OR, 3.5; 95%CI,; diabetes or obesity (OR, 12.6; 95%CI, and immunocompromise (OR, 7.03; 95%CI,. Conclusions: Children < 3 years with COVID-19 and comorbidities, especially diabetes or obesity, and immunocompromised patients have a higher risk of developing pneumonia.

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“…Señor Editor, Después de leer artículo de Rivas-Ruiz, et al 1 , percibimos ciertos errores y sugerimos su atención. La literatura evidencia que existen diferencias en el proceso de la enfermedad por coronavirus 2019 (COVID-19) entre los lactantes, niños y adolescentes dentro del grupo pediátrico como lo reportaron Panahi, et al 2 , donde los niños cursaban mayormente con fiebre y tos seca, mientras que los lactantes presentaron aumento de la frecuencia cardiaca.…”

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