Factores asociados al pronóstico de los pacientes pediátricos ventilados mecánicamente. Un estudio internacional

Farias, Júlio A.; Frutos‐Vivar, Fernando; Flores, Juan; Siaba, Alejandro; Retta, Alejandra; Fernández, A.; Baltodano, A.; Ko, Inja; Johnson, M. A.; Esteban, Andrés

doi:10.1016/s0210-5691(06)74565-x

Cited by 14 publications

(3 citation statements)

References 26 publications

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“…The observed difference is not clinically significant and the majority of these patients receive multiple treatments which modify heart rate and variations could also be explained by hypoxemia and increased respiratory work. However, we emphasize that, as observed in other studies, the severity of respiratory work, particularly respiratory rate was an indicator of treatment failure with a more specific behavior [6,7].…”

Section: Low Respiratory Infectionsupporting

confidence: 70%

Noninvasive Ventilation Outside Critical Care Units for Children with Severe Low Respiratory Infection: Is it a Potential Strategy for Critically Ill Children in Uruguay?

Alemán¹,

Giachetto²

2014

J Neonatal Biol

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Section: Low Respiratory Infectionsupporting

confidence: 70%

Noninvasive Ventilation Outside Critical Care Units for Children with Severe Low Respiratory Infection: Is it a Potential Strategy for Critically Ill Children in Uruguay?

Alemán¹,

Giachetto²

2014

J Neonatal Biol

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“…Comparing Ped-PVAP and the sum of VAT and VAP (2008 CDC definitions) in our cohort of children, we found their incidence to be similar, but we did not find a good clinical correlation: most VATs occur in patients with respiratory good status and do not meet Ped-VAE criteria. The impact of this group of VAT with good respiratory status on outcomes is null, so the key factor is hypoxaemia [25]. In addition to VAP, Ped-PVAP also includes VAT, which presents with hypoxaemia or clinical worsening in previously hypoxaemic children: these VATs have a real impact on outcomes, and they need to be treated in order to avoid patient deterioration.…”

Section: Discussionmentioning

confidence: 99%

Assessing prediction accuracy for outcomes of ventilator-associated events and infections in critically ill children: a prospective cohort study

Peña-López

Pujol

Campins

et al. 2018

Clinical Microbiology and Infection

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“…Reported mortality of children on MV in developed countries were 1.6 – 15% (4, 5, 7, 26), while mortality rate was higher in less developed countries 30–3% – 58.3% (3, 17). Prognosis of mechanically ventilated children was reported to be related to high PRISM score, and the presence of MODS in other studies (26, 27). Regarding the limitation of the study, the study did not include arterial blood gases (ABGs) parameters, or ventilator setting changes used in the study according to ABGs.…”

Section: Discussionmentioning

confidence: 98%

Mechanical ventilation practice in Egyptian pediatric intensive care units

Kamal

2017

Electron physician

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IntroductionMechanical ventilation is one of the indispensable tools in pediatric intensive care units. Few studies addressed the epidemiology of pediatric patients on mechanical ventilation and the frequently used modes of ventilation. This is the first study to describe the practice of mechanical ventilation (MV) in Egyptian pediatric intensive care units (PICUs).MethodsThis prospective observational study was conducted from January 2014 to December 2014 in two pediatric intensive care units at Cairo University Pediatric Hospital. The study included all children who were intubated and mechanically ventilated for more than 12 hours of admission. Pre-coded data was entered into the SPSS version 21 for data analysis. Comparison between groups was performed using Mann Whitney test for quantitative variables and Chi square with Fisher’s exact test for qualitative ones. Multivariate logistic regression model was conducted to explore the significant predictors for PICU mortality.ResultsIn total, 893 children were admitted and 293 were mechanically ventilated. The incidence of utilizing MV in children was 32.8%. Neurologic causes were the most common reasons for initiation of MV, with 114 (38.9%) cases. The most commonly preferred mode for initiation of MV is SIMV with PS. Complication occurred in 117 (39.9%) of the cases. The most commonly preferred method of weaning was PS with CPAP in 115/154 (74.7%) cases. Mortality occurred in 134/293 (45.7%) of patients. Duration of mechanical ventilation was significantly longer with neuromuscular diseases, and with the occurrence of complications (p<0.001). There was a significant relationship between mortality and higher PRISM III score, cardiovascular cases, sepsis, multiple organ dysfunction syndrome (MODS), ventilator-associated pneumonia (VAP), and with barotrauma.ConclusionsIn our practice, MV is used oftentimes with almost a third of admissions requiring intubation for different reasons. Most children are ventilated due to neurologic causes. This study paves the way for improving our knowledge of MV with avoiding the fatal complications.

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Factores asociados al pronóstico de los pacientes pediátricos ventilados mecánicamente. Un estudio internacional

Cited by 14 publications

References 26 publications

Noninvasive Ventilation Outside Critical Care Units for Children with Severe Low Respiratory Infection: Is it a Potential Strategy for Critically Ill Children in Uruguay?

Noninvasive Ventilation Outside Critical Care Units for Children with Severe Low Respiratory Infection: Is it a Potential Strategy for Critically Ill Children in Uruguay?

Assessing prediction accuracy for outcomes of ventilator-associated events and infections in critically ill children: a prospective cohort study

Mechanical ventilation practice in Egyptian pediatric intensive care units

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