Factores demográficos y comorbilidades asociadas a severidad de COVID-19 en un hospital chileno: el rol clave del nivel socioeconómico

Domínguez, Gaspar; Garrido, C. Mellado; Cornejo, María Alejandrina Nivela; Danke, Karen; Acuña, Mirta

doi:10.4067/s0034-98872021000801141

Cited by 4 publications

(4 citation statements)

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“…Similarly, a Brazilian retrospective study that included 74,991 fully vaccinated COVID-19 patients from February 2021 to January 2022 also reported a higher proportion of male cases compared with female cases [17]. In addition, a retrospective cohort study conducted among COVID-19 patients in Chile showed that male sex was strongly associated with a poor prognosis of COVID-19 [18].…”

Section: Discussionmentioning

confidence: 91%

Severe COVID-19 Outcomes in Five Latin American Countries in the Postvaccination Era

Silva Julian,

Spinardi,

Diaz-Puentes

et al. 2024

Viruses

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We conducted a multicountry retrospective study using data from COVID-19 national surveillance databases to analyze clinical profiles, hospitalization rates, intensive care unit (ICU) admissions, utilization of ventilatory support, and mortality rates in five Latin American countries in the context of COVID-19 vaccination implementation. We analyzed the sociodemographic characteristics, comorbidities, clinical outcomes, and vaccination status of laboratory-confirmed COVID-19 cases from January 2021 to December 2022. We calculated the yearly and quarterly hospitalization rates per 1000 confirmed COVID-19 cases and ICU admissions, use of mechanical ventilators, and mortality rates per 1000 hospitalized cases, with their corresponding 95% confidence interval (CI) of 38,852,831 confirmed COVID-19 cases. Rates of hospitalization, ICU admission, ventilatory support, and death were higher among males than among females (38.2 vs. 32.4, 148.4 vs. 117.7, 282.9 vs. 236.2, and 346.9 vs. 320.1 per 1000, respectively); higher in 2021 than in 2022 (50.7 vs. 19.9, 207.8 vs. 58.2, 441.5 vs. 114.9, and 352.5 vs. 285.2 per 1000, respectively); and in the >50 age group (range: 5.7–18.6, 20.1–71.5, 12.2–67.9, and 353.1–577.4, per 1000) than the <50 age group (range: 2.2–9.3, 5.4–33.2, 41.4–135.8, and 22–243.5 per 1000). Hypertension and diabetes mellitus were the most common comorbidities in Mexico and Colombia. Prevention and treatment strategies for these case profiles could bring benefits from a public health perspective.

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Section: Discussionmentioning

confidence: 91%

Severe COVID-19 Outcomes in Five Latin American Countries in the Postvaccination Era

Silva Julian,

Spinardi,

Diaz-Puentes

et al. 2024

Viruses

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“…El estudio analizo a un grupo de 1 381 pacientes que acudieron al SSU y dieron positivo por COVID-19 entre las gestiones 2021 y 2022 (a marzo), del grupo estudiado 53 personas fallecieron, lo que representa una mortalidad del 3,8% respecto a los casos confirmados (I.C. 95% 2,88 -4,99), valor menor a la letalidad (12,88%) registrada en el hospital el Carmen en Chile 15 , pero cercanas a las registradas en Ecuador en población con características socioculturales similares a Bolivia (8,59%), siendo mayor en hombres (6,86%) que en mujeres (3,35%). Así, la tasa de letalidad fue del 1,6%; superior a países como Italia (0,4%) y China (0,4%) 16 .…”

Section: Discussionunclassified

Factores asociados a mortalidad por COVID-19 en el Seguro Social Universitario de la ciudad de La Paz, 2021 – 2022

Tamayo-Caballero,

Navía-Bueno,

Alejo-Pocoma

et al. 2023

Rev. Cient. Memoria del Posgrado

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Objetivo: Determinar los factores asociados a mortalidad por COVID-19 en pacientes del Seguro Social Universitario de la ciudad de La Paz (S.S.U.) durante las gestiones 2021 y 2022. Material y Métodos: Estudio transversal analítico, realizado en el S.S.U. con pacientes mayores a 18 años que acudieron a consulta con resultado positivo de COVID-19 en las gestiones 2021 y 2022 (marzo), llegando a un total de 1381 casos. Los datos fueron recolectados a partir de datos administrativos. Se determinó el número de fallecimientos mediante frecuencias y se procedió a relacionar la ocurrencia de muerte con los factores de estudio, utilizando la prueba Chi-cuadrado (X2) y la medición de riesgo mediante Razón de Posibilidades (RP). Resultados: 53 personas fallecieron entre las gestiones 2021 y 2022 (marzo), lo que representa una mortalidad del 3,8% respecto a los casos confirmados (1 381). Están asociados a la mortalidad por COVID-19 el ser mayor de 60 años, ser hombre, tener un diagnóstico grave, el ingreso a UTI, asimismo es factor protector el hecho de estar vacunado. Conclusiones: La vacuna es un protector efectivo contra la muerte por COVID-19

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“…A recent study in 1141 Chilean patients showed that the frequency of obesity was 25.07%. Of these patients, 23.3% presented a serious evolution [ 25 ]. The contrast in the frequencies observed in patients with COVID-19 in global studies can be explained, at least in part, by the differences in the prevalence of obesity between populations [ 26 , 27 , 28 , 29 , 30 , 31 ].…”

Section: Development Of the Topicmentioning

confidence: 99%

“…In addition, studies have shown that obesity is associated with a higher risk of mortality among patients with COVID-19 and is higher in patients with class III obesity than in those with class I and II obesity [ 34 ]. Finally, by studying a cohort of 1141 cases confirmed by molecular biology, Domínguez et al [ 25 ] showed that obesity is a risk factor for severe disease (critical care and death) (OR 2.36; 95% CI 1.65–3.39), regardless of the effect of diseases, such as diabetes or chronic kidney disease.…”

Section: Development Of the Topicmentioning

confidence: 99%

Obesity as a Risk Factor for Severe COVID-19 in Hospitalized Patients: Epidemiology and Potential Mechanisms

et al. 2022

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SARS-CoV-2 infection is a global public health problem, causing significant morbidity and mortality. Evidence shows that obesity is a recognized risk factor for hospitalization, admission to critical care units, and the development of serious complications from COVID-19. This review analyzes the available epidemiological evidence that relates obesity to a higher risk of severity and mortality from COVID-19, examining the possible pathophysiological mechanisms that explain this phenomenon on a cellular and molecular level.

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Factores demográficos y comorbilidades asociadas a severidad de COVID-19 en un hospital chileno: el rol clave del nivel socioeconómico

Cited by 4 publications

References 0 publications

Severe COVID-19 Outcomes in Five Latin American Countries in the Postvaccination Era

Severe COVID-19 Outcomes in Five Latin American Countries in the Postvaccination Era

Factores asociados a mortalidad por COVID-19 en el Seguro Social Universitario de la ciudad de La Paz, 2021 – 2022

Obesity as a Risk Factor for Severe COVID-19 in Hospitalized Patients: Epidemiology and Potential Mechanisms

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