Factors affecting health-related quality of life in prostate cancer patients

Mickevičienė, Aušra; Vanagas, Giedrius; Ulys, Albertas; Jievaltas, Mindaugas; Smailytė, Giedrė; Padaiga, Žilvinas

doi:10.3109/00365599.2012.661765

Cited by 13 publications

(13 citation statements)

References 27 publications

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“…According to previous publications, quality of life generally depends on clinical status, such that quality of life decreases with disease severity (19,20). We therefore conducted this study with the goal of establishing whether clinical status is linked to differences in quality of life in patients with colorectal or stomach cancer and to what extent certain items on the commonly used EORTC QLQ C30 scale can serve to distinguish levels of quality of life related to health.…”

Section: Methodsmentioning

confidence: 99%

Relationship between quality of life and clinical status in patients with gastrointestinal cancer

Pedraza

Alexander-Sierra

Oliveros

2012

Rev. esp. enferm. dig.

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Background: previous studies with patients having cancer have shown that quality of life scores depend on the clinical stage of the disease (the more advanced the disease, the worst quality of life).Methods: in a prospective study we studied 317 patients with gastric or colorectal cancer attending the Instituto Nacional de Cancerología between 2010 and 2011; the patients completed the EORTC QLQ-C30 before receiving treatment. This instrument measures quality of life in 15 domains. Scores of each domain were compared according to tumor stage. Differential Item Functioning was measured across neoplasm staging and tumor localization.Results: 145 patients (45.7%) were diagnosed with colorectal cancer. According to clinical staging, differences in quality of life scores were observed in 4 of 15 domains (physical and social functioning, anorexia). Most of the differences in quality of life domains depended on tumor localization (patients with colorectal cancer had the highest scores in quality of life) and sex (women reported better scores). These differences seemed to be independent of item properties. The construct was more adequately measured with items that explore the construct using a general approach.Conclusion: in this group of patients with colorectal and gastric cancer quality of life scores were more related with tumor localization than with clinical stage.

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Section: Methodsmentioning

confidence: 99%

Relationship between quality of life and clinical status in patients with gastrointestinal cancer

Pedraza

Alexander-Sierra

Oliveros

2012

Rev. esp. enferm. dig.

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“…The QoL assessment plays a key role in the evaluation and treatment of patients [10], especially it is seen as very important indicator of quality of care for cancer patients [11]. Most studies reporting QoL outcomes are based on trials [12,13], where inclusion and exclusion criteria limit external validity of results and does not exhibit "real life" differences among stage and treatment groups.…”

Section: Does Quality Of Life Of Prostate Cancer Patients Differ By Smentioning

confidence: 99%

“…Although the awareness by physicians and patients has increased, there is still a paucity of objective data of QoL for cancer stages and available PCa treatment options, primarily due to the relative lack of large prospective studies. In general it is expected that the increase in early detection and treatment can result a better tolerance of the presently available therapeutic procedures and a higher QoL of PCa patients [18,11,[20][21][22][23][24][25].…”

Section: Comparison To Previous Studiesmentioning

confidence: 99%

Does quality of life of prostate cancer patients differ by stage and treatment?

Vanagas

Mickevičienė

Ulys

2012

Scand J Public Health

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“…Theoretically, the results of the QoL survey may be different for different periods because of the influence of several factors, including social, economic, weather/seasonal, and mass media. Factors affecting QoL scores might also include education level, monthly expenses for treatment, and disease stage (17). However, the large population-based cohort in this study may have confined this limitation.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and functional outcomes 10 years after laparoscopic radical prostatectomy

Wang

Eriksson

2013

Upsala Journal of Medical Sciences

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Background Minimally invasive laparoscopic radical prostatectomy (LRP) has proven equally effective as open surgery in terms of cancer control and peroperative complication rate with less bleeding and postoperative pain. However, long-term follow-up data after LRP are scarce, especially as related to quality of life (QoL).Aim To compare QoL and functional outcomes at least 10 years after LRP with a population-based control group matched for age and region.Methods Follow-up data were obtained by mailed questionnaires from patients who responded anonymously to five international questionnaires (EQ-5D, QLQ-C30, QLQ-PR25, IPSS, and IIEF). We collected self-reported outcome data directly from 49 patients who underwent LRP more than 10 years ago in our centre. The results of the patients' overall QoL and urinary continence rates were compared with 918 controls matched for region and age.Results Forty-two patients (86%) and 808 (88%) controls reported having no urinary leakage. Only 11 patients (24%) still had sexual activities 10 years after LRP, and three were without erectile dysfunction. There was no difference in four of five statements of the self-assessed QoL questionnaires between the LRP and control group. Anxiety level was higher in the LRP group (44%) than in the control group (23%).Conclusion Patients reported high self-assessed QoL, although they also reported low sexual activity 10 years after LRP. Prevalence of urinary leakage was similar in both groups. However, anxiety was more common in LRP patients.

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Factors affecting health-related quality of life in prostate cancer patients

Abstract: Significant predictors for higher QoL scores were education level, own monthly expenses for treatment and disease stage. Patients with undisclosed disease stage more often had higher QoL scores.

Cited by 13 publications

References 27 publications

Relationship between quality of life and clinical status in patients with gastrointestinal cancer

Relationship between quality of life and clinical status in patients with gastrointestinal cancer

Does quality of life of prostate cancer patients differ by stage and treatment?

Quality of life and functional outcomes 10 years after laparoscopic radical prostatectomy

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