Factors affecting the incidence and outcome of <i>Trueperella pyogenes</i> mastitis in cows

Abstract

The main factors affecting the outcome of Trueperella pyogenes (T. pyogenes) mastitis were examined through a survey of diagnostic data and interviews relating to the occurrence of T. pyogenes mastitis in 83 quarters from 82 Holstein cows between August 2012 and April 2014. Ultimately, one cow was sold during the examination, and 82 quarters from 81 cows were used for analysis on prognosis. T. pyogenes mastitis occurred year round in both lactating and dry cows. The incidence of T. pyogenes mastitis did not significantly differ by month or show seasonality in either lactating or dry cows. Therefore, the occurrence of T. pyogenes mastitis also differed from that of summer mastitis. The 1-month survival rate of infected cows was 64.6% (53/82), and the recovery rate of quarters with T. pyogenes mastitis was 14.6% (12/82). Bivariate logistic regression analysis was performed with survival and culling of infected cows as objective variables and with recovery and non-recovery of quarters with T. pyogenes mastitis as objective variables. The severe cases were significantly culled (odds ratio, 16.30) compared to mild cases, and the status of quarters didn’t recover (odds ratio, 6.50). The results suggest that mild to moderate symptom severity at the time of onset are the main factors affecting outcomes in cows and recovery of quarters infected with T. pyogenes mastitis. Further, high level of NAGase activity also suggested the potential use as an indicator of culling of cows with T. pyogenes mastitis.

Pathogenicity and Virulence of Trueperella pyogenes: A Review

“…The prevalence of T. pyogenes isolation may differ, depending on a host species and a geographic region. The majority of published data concerns T. pyogenes infections in food animals and comes from Europe [21,33,34,35,36,37,38], China [39,40,41,42,43], Japan [44,45], Brazil [30,46], and the United States [47,48,49,50]. In livestock, the diseases caused by T. pyogenes generate significant economic losses, mainly in cattle and swine breeding, causing a reduction of meat and milk yield, as well as decreased reproductive efficiency and sometimes the necessity to cull diseased animals.…”

Subcutaneous abscess caused by Trueperella pyogenes in a bovine in the Western Amazon: case report

“…In infections by T. pyogenes that culminate in arthritis, osteomyelitis, abortion, metritis, orchitis, omphalitis, bronchopneumonia and liver abscesses, the prognosis is established as reserved to poor (KONTTURI et al, 2019;PIERSANTI et al, 2019). However, resolution is simpler in cases of mastitis and subcutaneous abscess (ISHIYAMA et al, 2017). The prognosis in the present case was favorable, possibly due to the good nutritional status of the animal, the gateway through the cutaneous tissue with no systemic dissemination and the effectiveness of the therapy employed (GIUFFRIDA; BIGNARD, 2011; GALÁN-RELAÑO et al, 2019).…”

“…Due to its pyogenic, opportunistic characteristic (taking advantage of a gateway), T. pyogenes causes suppurative infection in domestic and wild animals (RISSETI et al, 2017;ÇEÇEN et al, 2018;ROGOVSKYY et al, 2018), although virulence factors have not been fully elucidated (RISSETI et al, 2017;LIU et al, 2018;TAMAI et al, 2018). The evolution of the disease is related to cases of mastitis, arthritis, interdigital phlebitis, osteomyelitis, abortion, metritis, orchitis, omphalitis and bronchopneumonia as well as subcutaneous abscess or abscess in parenchymal tissues, with a variable prognosis (CAFFARO et al, 2014;ISHIYAMA et al, 2017;WARETH et al, 2018;KONTTURI et al, 2019;PIERSANTI et al, 2019).…”

Studies on Trueperella Pyogenes Isolated from an Okapi (Okapia johnstoni) and A Royal Python (Python Regius)

“…However, T. pyogenes is also an important opportunistic pathogen that causes mastitis, abortion and a variety of diverse pyogenic infections in livestock, including cattle, sheep, goats, horses, and pigs (2)(3)(4). In cattle, T. pyogenes appears to be responsible for infections of the reproductive tract (5) and the mammary gland (6), as well as cases of pneumonia and liver abscessation of bovines and small ruminants (7). In swine, T. pyogenes is well known as a causative agent of different types of in ammation in various organs including the lung, heart, joints, mammary glands, and in the reproductive tract (8,9).…”