Factors affecting the outcomes of direct pulp capping using Biodentine

Abstract

IntroductionThis study aimed to evaluate the prognostic value of factors with regard to the treatment outcome of direct pulp capping using Biodentine (Septodont, Saint-Maur-des-Fossés, France), in permanent teeth in which the pulps were exposed during caries removal.MethodsBetween 2010 and 2014, 112 teeth with deep carious lesions underwent direct pulp capping. The patients were followed up at 2–3 months and 1–1.5 years with a routine examination on both recall visits. Periapical radiographs were taken at 1–1.5 years. Lack of patient complaints, positive reactions to cold and electric testing, no sensitivity to percussion, and no widening of the periapical ligament indicated success. The Fisher exact test was used for statistical analysis. The significance level was P = .05.ResultsEighty-six teeth were available for 1–1.5 years follow-up. The overall success rate was 82.6%. Only age had a significant effect on the pulpal survival rate: the success rate was 90.9% in patients younger than 40 years and 73.8% in patients 40 years or older (P = .0480). Sex, initial or secondary caries treatment, occlusal or cervical/proximal caries, delayed placement of permanent filling, tooth position, and arch type did not influence the outcome.ConclusionsA patient’s age influenced the outcome of direct pulp capping using this new calcium silicate cement.Clinical relevanceAsymptomatic vital permanent teeth with cariously exposed pulp can be treated successfully by direct pulp capping using Biodentine.

Bio-Inductive Materials in Direct and Indirect Pulp Capping—A Review Article

“…Other studies also support claims of Biodentine's and MTA's superiority over calcium hydroxide in terms of success rate in pulp capping procedures [107,108]. Another study reported that the success rate of DPC with BD is 90.9% in patients younger than 40 and 73.8% in patients 40 or older [109]. It is worth emphasizing that patient's age significantly influences the clinical outcome of this vital pulp therapy and needs to be taken into consideration when choosing successful treatment.…”

Analysis of the Activity and Expression of Cyclooxygenases COX1 and COX2 in THP-1 Monocytes and Macrophages Cultured with BiodentineTM Silicate Cement

“…Biodentine TM (Septodont, Saint Maur des Fsses, France) is an example of a material based on hydrated calcium silicate. It shows odontotropic properties, that is, it stimulates the formation of reactive and reparative dentin and helps maintain proper sensitivity of the dental pulp [6][7][8][9]. The efficacy of the biological treatment of the pulp is higher in the younger patients as compared to the older patients [8].…”

“…It shows odontotropic properties, that is, it stimulates the formation of reactive and reparative dentin and helps maintain proper sensitivity of the dental pulp [6][7][8][9]. The efficacy of the biological treatment of the pulp is higher in the younger patients as compared to the older patients [8]. This material is also used for sealing root perforation [9,10].…”

“…However, from the clinician's perspective, every material used to fill a tooth, even those showing the optimal chemical parameters, is in fact a foreign body introduced to the organism of the host. Therefore, apart from the chemical parameters of such materials, equally important is the so-called biocompatibility of such materials [1,5,7,8].…”

“…As a result of this, the pulp's functional status as well as the integrity of the barrier preventing the entry of bacteria are preserved. Additionally, the pulp-dentin complex is a basic unit for the assessment of the biological risk connected with applying materials to the exposed pulp during the biological treatment [7,8]. The pulp of a healthy tooth has cells involved in immune reactions such as macrophages, lymphocytes, plasma cells and mast cells.…”