Factors affecting the separation of inorganic metal cations by capillary electrophoresis

Weston, Andrea; Brown, Phyllis R.; Jandík, Petr; Jones, William; Heckenberg, A.L.

doi:10.1016/0021-9673(92)80297-8

Cited by 183 publications

(50 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The equivalent ionic conductivities are directly related to the electrophoretic mobilities [2], pq, of the ions:…”

Section: Types Of Flowmentioning

confidence: 99%

“…The complete complexation of metals with ligands to form anions has been investigated [2,25,26]. Aguilar et al [27] and Buchberger et al [28] have separated metal-cyanide complexes in CE followed by direct W detection.…”

Section: Direct Detectionmentioning

confidence: 99%

“…~ A variation of this approach is to add the complexing ligand to the carrier electrolyte [2,29]. This establishes an equilibrium between the free and complexed metal ions.…”

Section: Direct Detectionmentioning

confidence: 99%

“…Weston et al [70] Shi and Fritz [72] reported being able to separate K+ and NH,' by adding 1 &crown-6 ether to the lactate buffer. They also investigated the effect of methanol on the separation.…”

Section: Weak Complexing Agentsmentioning

confidence: 99%

“…Weston et al [69,70] also investigated the role of pH. They found that lowering the pH increased the migration times due to the decreasing electroosmotic flow.…”

Section: Phmentioning

confidence: 99%

See 4 more Smart Citations

Separation of ions in acidic solution by capillary electrophoresis

Thornton

1997

View full text Add to dashboard Cite

“…The equivalent ionic conductivities are directly related to the electrophoretic mobilities [2], pq, of the ions:…”

Section: Types Of Flowmentioning

confidence: 99%

Section: Direct Detectionmentioning

confidence: 99%

“…~ A variation of this approach is to add the complexing ligand to the carrier electrolyte [2,29]. This establishes an equilibrium between the free and complexed metal ions.…”

Section: Direct Detectionmentioning

confidence: 99%

Section: Weak Complexing Agentsmentioning

confidence: 99%

“…Weston et al [69,70] also investigated the role of pH. They found that lowering the pH increased the migration times due to the decreasing electroosmotic flow.…”

Section: Phmentioning

confidence: 99%

See 3 more Smart Citations

Separation of ions in acidic solution by capillary electrophoresis

Thornton

1997

View full text Add to dashboard Cite

Detection in capillary electrophoresis

2000

View full text Add to dashboard Cite

Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds

Durkin

Foley

2000

Electrophoresis

View full text Add to dashboard Cite

The concept of dual opposite injection in capillary electrophoresis (DOI-CE) for the simultaneous separation, under conditions of suppressed electroosmotic flow, of anionic and cationic compounds with no bias in resolution and analysis time, is extended to a higher pH range in a zone electrophoresis mode (DOI-CZE). A new DOI-CE separation mode based on electrokinetic chromatography is also introduced (DOI-EKC). Whereas conventional CZE and DOI-CZE are limited to the separation of charged compounds with different electrophoretic mobilities, DOI-EKC is shown to be capable of separating compounds with the same or similar electrophoretic mobilities. In contrast to conventional EKC with charged pseudostationary phases that often interact too strongly with analytes of opposite charge, the neutral pseudostationary phases appropriate for DOI-EKC are simultaneously compatible with anionic and cationic compounds. This work describes two buffer additives that dynamically suppress electroosmotic flow (EOF) at a higher pH (6.5) than in a previous study (4.4), thus allowing DOI-CZE of several pharmaceutical bases and weakly acidic positional isomers. Several DOI-EKC systems based on nonionic (10 lauryl ether, Brij 35) or zwitterionic (SB-12, CAS U) micelles, or nonionic vesicles (Brij 30) are examined using a six-component test mixture that is difficult to separate by CZE or DOI-CZE. The effect of electromigration dispersion on peak shape and efficiency, and the effect of surfactant concentration on retention, selectivity, and efficiency are described.

show abstract

Factors affecting the separation of inorganic metal cations by capillary electrophoresis

Cited by 183 publications

References 18 publications

Separation of ions in acidic solution by capillary electrophoresis

Separation of ions in acidic solution by capillary electrophoresis

Detection in capillary electrophoresis

Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds

Contact Info

Product

Resources

About