Factors Affecting the Success of  Multi Drug Resistance (MDR-TB) Tuberculosis Treatment in Residential Surakarta

Widyasrini, Elisabeth Ria; Probandari, Ari; Reviono,

doi:10.26911/jepublichealth.2017.02.01.05

Cited by 4 publications

(5 citation statements)

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“…Our study found that male were 1.24 times to have successful treatment compared to women with p = 0.005. Studies in Africa, Bangladesh, and Syria found that women were more difficult to reach health services because of cultural barriers and low levels of education [ 18 ]. However, this study did not evaluate further regarding education, culture, and socioeconomics role.…”

Section: Discussionmentioning

confidence: 99%

Factors affecting outcome of longer regimen multidrug-resistant tuberculosis treatment in West Java Indonesia: A retrospective cohort study

et al. 2021

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Background Multidrug-resistant tuberculosis had high treatment failure and mortality. Success rate of treatment currently 56% at global level, 48% in Indonesia and 36% in West Java province, the most populated province and surround Jakarta, the capitol of Indonesia. Objective This study aimed to evaluate factors affecting success of multidrug-resistant tuberculosis treatment in patients using longer treatment regimen in West Java Indonesia. Methods This was a retrospective cohort study of multidrug-resistant tuberculosis patients treated with longer regimen at Hasan Sadikin General Hospital from January 2015 to December 2017. Potential risk factors associated with the treatment outcome were analyzed using multiple logistic regression. Results A total of 492 patients were enrolled during the study period. Fifty percents multidrug-resistant tuberculosis patients had successful treatment outcome. Age ≤45 years, male, normal body mass index, no previous tuberculosis treatment, culture conversion ≤2 months, acid fast bacilli sputum smear ≤+1 were independent factors associated with increased treatment success. Sputum culture conversion ≤2 months was the major factor affecting successful outcome (RR 2.79; 95% CI: 1.61–4.84; p-value<0.001). Human Immunodeficiency Virus infection, chronic kidney disease, and cavitary lesion were independent risk factors for unfavourable outcome. Conclusion Age, gender, body mass index, tuberculosis treatment history, time of sputum conversion, acid fast bacilli sputum smear, HIV infection, chronic kidney disease, and cavitary lesion can be used as predictors for longer multidrug-resistant tuberculosis treatment regimen outcome.

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Section: Discussionmentioning

confidence: 99%

Factors affecting outcome of longer regimen multidrug-resistant tuberculosis treatment in West Java Indonesia: A retrospective cohort study

et al. 2021

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“…Pada penderita yang telah memulai pengobatan sejak tahun 2015, keberhasilan pengobatannya hanya sebesar 55%, sedangkan 15% lainnya meninggal, 14% mengalami drop out pengobatan, 8% mengalami kegagalan pengobatan, dan 7% tidak ada informasi terkait hasil pengobatan (WHO, 2018). (Widyasrini & Probandari, 2015). Umur penderita TB MDR yang lebih tua cenderung memiliki risiko mengalami drop out pengobatan TB MDR dan ketidakberaturan dalam pengobatan karena usia tua membutuhkan dukungan tambahan untuk menjalani pengobatan TB MDR (Wu et al, 2013).…”

Section: Pendahuluanunclassified

“…Akantetapitingkat pendidikan tidak terbukti berhubungan dengan kejadian drop out pengobatan TB MDR (95% CI= 0,87 -2,12; p= 0,180) (Widyasrini & Probandari, 2015). Penelitian laindengan nilai p sebesar 0,306 untuk kategori tingkat pendidikan dasar yang artinya tidak ada hubungan antara tingkat pendidikan dasar dengan kejadian putus berobat TB paru, dan untuk kategori tingkat pendidikan menengah dihasilkan nilai p sebesar 0,323, sehingga tidak ditemukan hubungan yang signifikan antara tingkat pendidikan menengah dengan kejadian putus berobat TB paru.…”

Section: Pendahuluanunclassified

“…Hubungan baik dalam keluarga mempengaruhi keberhasilan pengobatan (Morris et al, 2014). Penelitian lain menunjukkan bahwa dukungan keluarga, yang meliputi dukungan emosional (OR = 0,89; 95% CI = 0,567 hingga 1,42; p = 0,65), dukungan apresiasi (OR = 1,04; 95% CI = 0.54 hingga 2,03; p = 0,90), dukungan informasi (OR = 1,16 ; 95% CI = 0,75 hingga 1,78; p = 0,49), dan dukungan instrumental (OR = 1,01; CI 95% = 0,69 hingga 1,45; p = 0,985) tidak berhubungan dengan keberhasilan pengobatan MDR-TB (Widyasrini & Probandari, 2015).…”

Section: Pendahuluanunclassified

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Drop Out Pengobatan Pada Tuberkulosis Multidrug Resistant (Tb Mdr) Di Kota Semarang

Amala

Cahyati

2021

QJK

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Angka kesembuhan (Cure Rate) pengobatan TB MDR di Kota Semarang dalam kurun waktu 5 tahun terakhir tidak pernah mencapai target nasional. Di Kota Semarang, terdapat 182 kasus TB MDR dalam kurun tahun 2016-2019. Tujuan penelitian ini adalah untuk mengetahui faktor- faktor yang berhubungan dengan kejadian drop out pengobatan TB MDR di Kota Semarang. Jenis penelitian ini adalah observasional analitik dengan menggunakan rancangan penelitian case control. Teknik pengambilan sampel menggunakan total sampling sebanyak 20 kasus dan 20 kontrol. Instrumen yang digunakan berupa kuesioner terstruktur dan panduan wawancara. Data dianalisis secara univariat, bivariat, dan multivariat menggunakan program SPSS. Hasil menunjukkan bahwa terdapat hubungan antara umur responden (OR= 4,63; 95% CI= 1,02-21,01), dukungan keluarga (OR=6,00; 95% CI= 1,46-24,69), peran PMO (OR=4,33; 95% CI= 1,15-16,32) terhadap kejadian drop out pengobatan Tuberkulosis Multidrug Resistant (TB MDR) di Kota Semarang.

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“…33 Selain itu, emotional support yaitu kasih sayang, kepedulian, dan kepercayaan dari keluarga akan meningkatkan kepercayaan diri pasien sehingga kesuksesan berobat akan tinggi. 34…”

Section: Hasil Dan Pembahasanunclassified

Model Tatalaksana Komprehensif Tuberculosis Multidrug-Resistant (TB-MDR) Melalui Pendekatan Provider Pelayanan Kesehatan

Irawansa

Bhaskoro

Maulana

et al. 2020

comphi

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Introduction: Tuberculosis is a highly contagious disease and requires long-term treatment and large amounts of medication. This can affect the high risk of Multidrug-Resistant Tuberculosis (MDR-TB). A health service approach in providing comprehensive management including promotive, preventive, curative, and rehabilitative is very necessary to overcome these cases. Aim of study: This article aims to determine interventions that can be carried out by health services in preventing the occurrence of multidrug-resistant tuberculosis (MDR-TB). Method: The method used is a literature review through national to international journals that examine the interventions that can be carried out by health services in preventing MDR-TB. The articles or data sources that have been obtained will be compared with one another so that the factors that most influence the occurrence of MDR-TB can be found. Results and Discussion: The literature search results show that health workers, especially doctors, have an important role in managing MDR-TB cases. Management of MDR-TB in a comprehensive manner is carried out through promotive, preventive, curative, and rehabilitative programs through a health service provider approach. Educational activities regarding TB, MDR-TB, or the possibility of drug resistance are important to do to prevent new cases of MDR-TB. Curative treatment is carried out to improve mental and social health. Furthermore, rehabilitative efforts are carried out as a means to improve health status recovery for MDR-TB sufferers. Conclusion: Health service providers can improve facilities, they can carry out promotive, curative rehabilitative management to reduce the incidence of MDR-TB.

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Factors Affecting the Success of Multi Drug Resistance (MDR-TB) Tuberculosis Treatment in Residential Surakarta

Cited by 4 publications

References 6 publications

Factors affecting outcome of longer regimen multidrug-resistant tuberculosis treatment in West Java Indonesia: A retrospective cohort study

Factors affecting outcome of longer regimen multidrug-resistant tuberculosis treatment in West Java Indonesia: A retrospective cohort study

Drop Out Pengobatan Pada Tuberkulosis Multidrug Resistant (Tb Mdr) Di Kota Semarang

Model Tatalaksana Komprehensif Tuberculosis Multidrug-Resistant (TB-MDR) Melalui Pendekatan Provider Pelayanan Kesehatan

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