Factors Associated with Adherence to Anti-Hypertensive Treatment in Pakistan

Hashmi, Saman K.; Afridi, Maria B.; Abbas, Kanza; Sajwani, Rubina A.; Saleheen, Danish; Frossard, Philippe; Ishaq, Mohammad; Ambreen, Aisha; Ahmad, Usman

doi:10.1371/journal.pone.0000280

Cited by 184 publications

(261 citation statements)

References 31 publications

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“…Similarly in an Iranian study by Hadi (2004) older patients were more and in a study from Iraq, the compliance was highest among patients aged 70 years and more (78%) followed by those <30-year-old (64%), and females were significantly more compliant than males. 22,24 Another study carried out in Pakistan among 460 hypertensive, showed that adherence increases with age and highest mean adherence rate was in the age group of 70-80 years. 23 Our study showed significant association with gender and marital status to the level of adherence.…”

Section: Discussionmentioning

confidence: 99%

Medication adherence and health belief model among hypertensive patients attending rural health centres of a tertiary care hospital in South India

Shameena

Badiger

Kumar

2017

Int J Community Med Public Health

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Background: Medication adherence is a growing concern to healthcare systems as non-adherence to pharmacotherapy has been associated with adverse outcomes and higher costs of care. Objective: To assess the determinants of Patient’s adherence to Hypertensive medication and to evaluate the levels of adherence based on Health belief Model.Methods: A cross-sectional study conducted in the OPDs of Rural Health Centres of a tertiary care hospital over a period of 4 months(April’16 –July’16) using a semi-structured and validated questionnaire which contain information on demographic characteristics, medication and health related facility and Health Belief Model. All hypertensives taking medication for more than 6 months were included in this study. Medication Adherence was assessed using the Morisky Medication Adherence Scale-8(MMAS-8).Statistical Analysis: Data was analysed using SPSS and P value <0.05 was considered statistically significant.Results: Out of 300 patients, 114 were males and 186 were females. The level of Adherence was 23% in our study subjects. Gender (0.05), Religion (0.02), Marital status (0.035), Socioeconomic status (p=0.000) and Frequency of medication (p=0.000) had association with adherence. Based on health belief model, perceived severity (p=0.000), perceived susceptibility (p=0.000), perceived benefit (p=0.000), perceived barrier (p=0.000), Cue to action (p=0.025) and self-efficacy (p=0.00) had association with adherence.Conclusions: Patients Knowledge, understanding and perception can improve the adherence to medication. The results of our study can be used for better treatment of Hypertension.

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Section: Discussionmentioning

confidence: 99%

Medication adherence and health belief model among hypertensive patients attending rural health centres of a tertiary care hospital in South India

Shameena

Badiger

Kumar

2017

Int J Community Med Public Health

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“…24 Studies shown no association of compliance with age and sex, but for literacy. 25 The present study has shown significant increase in compliance scores of all study subjects as well as in case of compliant and non-compliant patients after educating the patients about hypertension (Table 2, Figure 1) 19,20,21,[26][27][28][29] One study however could not find significant effect of education of hypertensive patients through mailing education packets, on mildly uncontrolled hypertension, but significant improvement in patient knowledge, home monitoring and satisfaction was observed. 30 In our study one to one verbal communication in the language of the patient probably proved more beneficial in improving compliance.…”

Section: Discussionmentioning

confidence: 67%

Impact of awareness about hypertension on compliance to antihypertensive medication

Gupta

Sood³

2018

Int J Basic Clin Pharmacol

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INTRODUCTIONHypertension (defined as: systolic B.P.>=130mm Hg; diastolic B.P.>=80mm Hg) is a condition in which arterial B.P. is chronically elevated.1 It is the commonest cardiovascular disorder, posing a major public health challenge, a major risk factor for cardiovascular mortality and accounts for 20-50% of all deaths. 2 Raised blood pressure is responsible for 60% of strokes and 50% of coronary ABSTRACT Background: Hypertension, a common cardiovascular disorder accounts for 20-50% of all deaths. This risk can be greatly ameliorated by creating awareness about disease and its effective treatment alongside regular medical check-ups. Therapeutic failures result from patient non-compliance, manifested as intentional or unintentional errors in dosage or schedule, overuse or underuse of prescribed drugs and early termination of therapy. Adherence is helpful for management of hypertension and cost minimization. Non-adherence to the drug treatment is an important factor for uncontrolled hypertension and its complications. Methods: Patients were interviewed individually after taking informed consent, using pretested, predesigned, self-administered and closed ended questionnaire both before and 4 weeks after creating awareness about hypertension and its complications. Compliance measured by self-reporting in which knowledge of the patient about number of antihypertensive drugs being used, formulations of drugs, frequency of administration, duration of taking the drugs and knowledge of complications due to uncontrolled and untreated hypertension were assigned 1 score each. Patient having score of at least 4 out of total 5 was considered compliant. Results: No significant association of compliance with demographic and other variables like age, sex, marital status, economic status, education, urbanization, duration of treatment and drug procurement were noted. A significant increase in compliance in patients on antihypertensive medication was found 4 weeks after creating awareness about hypertension and its complication. A significant increase in compliance scores was also seen in non-compliant patients showing their shifting from non-compliance to compliance group. Overall compliance increased from 59.38% to 84.38%. A percentage decrease from 58.82% to 25% in patients having uncontrolled hypertension was also observed after the awareness about hypertension. Conclusions: Demographic variables, duration of hypertension and drug procurement have no significant effect on compliance to antihypertensive medication. There is persistence and improvement in compliance to antihypertensive medications after an education of the patients about hypertension and its complications.

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“…Baune et al, 26 showed a significant correlation between education and quality of life (QOL) among patients with hypertension in Gaza Strip and hypothesized that educational interventions would be essential in preventing high blood pressures and consequent mortality. Knowledge of hypertension significantly affected adherence in Hashmi et al 27 study sample. Patients who were aware of the association between certain risk factors for hypertension, such as high salt intake, stress and a positive family history, had better adherence compared to those who with poorer knowledge.…”

Section: Discussionmentioning

confidence: 88%