Factors associated with adults' perceived need to vaccinate against hepatitis B in rural China

Abstract

Hepatitis B virus (HBV) infection is a serious public-health issue in China. While the hepatitis B vaccine is effective in preventing HBV infection, the HBV vaccination coverage rates among Chinese adults remain low. From a survey of rural adults from 7 provinces in China, we identified a unique HBV at-risk group: rural adults who had no history of HBV vaccination and had no plan to HBV vaccinate in the future. We divided this 'no history-no plan' group into those who identified No-need to vaccinate and those that perceived a Need to vaccinate (even if they had no plan to do so). We found age, marital status, health status, perceived HBV infection environment, perceived HBV infection risk and perceived HBV infection severity explained differences between the 'No-need' and 'Need" to HBV vaccinate groups. Education, occupation and knowledge of hepatitis B and HBV transmission were not associated with HBV vaccination need. Our results showed that free HBV vaccinations and reimbursement for vaccinating could significantly increase the HBV vaccinate take-up rate for both Need and No-need rural adults. A tailored public health HBV campaign, especially targeting the No-need subgroup, would increase vaccination rates by better informing rural adults about HBV transmission routes, the dangers of HBV infection, the effectiveness of HBV vaccinations and the safety of HBV vaccinations.

Knowledge, Preference, and Willingness to Pay for Hepatitis B Vaccination Services among Woman of Reproductive Age in Vietnam

“…In this study, we found that women with lower levels of education had high rate of willingness to vaccinate, but this association was not statistically significant when being adjusted in regression model. Previous studies in China were in line with us when it was found that education was negatively correlated with the need of HBV vaccine and willingness to pay for it [16, 22]. The reason of this phenomenon is unclear.…”

Barriers to and Facilitators of Hepatitis B Vaccination among the Adult Population in Indonesia: A Mixed Methods Study

“…Logistic regression was used to assess the association between the outcome variable (vaccine uptake) and the independent variables (sociodemographics, knowledge, and risk perception regarding hepatitis B infection). First, all independent variables that had an association with the outcome variable based on previous studies [ 12 , 15 , 23 , 24 , 25 , 26 , 27 , 28 ] were included into a univariable logistic regression model, and crude odds ratios (COR) were obtained (model 1, Table 1 ). Subsequently, a multivariable logistic regression was applied to calculate mutually adjusted odds ratios (AOR) (model 2, Table 1 ).…”

Intention to Hepatitis B Vaccinate: Evidence from Migrant Workers in Tianjin, China

“…Previous studies have shown that the intention to receive the HBV vaccine is affected by individual's knowledge of HBV and the HB vaccine [11 12]. Research showed that migrant workers have poorer cognition of HBV and the HB vaccine, and a higher HBV prevalence rate, than permanent workers due to their poorer education and health awareness levels, living in groups and lower accessibility to health care [13][14][15][16]. Previous Chinese studies have also identified an individual's knowledge and cognition of HB and the HB vaccine as key factors explaining HB vaccination behavior, but these studies only employed partial measures of HBV cognition [17][18][19].…”