Factors Associated with CKD in the Elderly and Nonelderly Population

Abstract

SummaryBackground and objectives The risk factors for CKD in different age groups remain unknown. This communitybased study aimed to identify the risk factors for CKD in elderly and nonelderly patients.Design, setting, participants, & measurements A multistage sampling survey for CKD was conducted in 2007 in Kaohsiung County, an area with the highest prevalence of dialysis in the world. CKD was defined as proteinuria in at least the microalbuminuric stage or an estimated GFR (eGFR) of ,60 ml/min per 1.73 m 2 . The factors for CKD in elderly and nonelderly patient groups were identified (with age 60 years as a cutoff value).Results The analyses included 3352 participants, of whom 687 had CKD. The weighted prevalence of CKD was 19.4% (95% confidence interval [CI], 18.0%-20.7%). Elderly patients typically presented with low eGFR and nonelderly patients, with proteinuria. Age, annual income, use of oral analgesics, metabolic syndrome, hyperuricemia, and hemoglobin were risk factors for CKD in both age groups. In elderly patients, risk factors were medical history of diabetes mellitus, CKD, stroke, and not using analgesic injection (odds ratios [

Risk factors of gender for renal progression in patients with early chronic kidney disease

“…[44] Annual income has been reported as potential risk factors for CKD. [33] However, our results showed that poor lipid control did not influence the risk of renal progression. In agreement with previous studies, lipid control parameters, namely total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and serum triglycerides, were not associated with severe renal progression outcomes.…”

“…A logistic regression model was used for exploring the risk factors affecting renal progression. The potential confounders were selected from demographic characteristics, [33,34] clinical variables, [13,35,36] physical examination variables, [17,37,38] laboratory test variables, [39,40] and health-related behaviors [19,20,41] associated with renal progression. Stepwise logistic regression analysis was performed to adjust for potential confounders.…”

Hepatitis C Virus Infection Increases the Risk of Developing Chronic Kidney Disease: A Systematic Review and Meta-Analysis

“…We retrieved 25 studies that met our inclusion criteria, of which two [16,17] reported outcomes from the same cohort and were excluded; a total of 23 studies were retrieved. The studies were published in 17 various articles [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34] and carried out in 4 countries ( Fig.…”

Association of herbal and dietary supplements with progression and complications of chronic kidney disease: A prospective cohort study

“…Guidelines for CKD management suggest avoiding herbal medicines containing aristolochic acid and using dietary supplements only under the supervision of a doctor or pharmacist . However, there are limited high quality studies to support such guidelines, particularly in patients with CKD and inconsistencies exist in the reports of associations between herbal medicine and either CKD or end‐stage renal disease (ESRD) . Tsai et al .…”

“…(2009) found a strong association between Chinese herbal medicine and ESRD (odds ratio (OR) 6.26, 95% confidence interval (CI) 3.85–10.19), while Lin et al . (2013) reported no association between Chinese herbal medicine and CKD . Two cross‐sectional studies in Thailand and Taiwan showed weak associations between herbal medicine and CKD (Thailand: adjusted OR 1.20, 95%CI 1.02–1.42, and Taiwan: adjusted OR 1.40, 95%CI 1.20–1.70) .…”