2016
DOI: 10.1038/srep25276
|View full text |Cite
|
Sign up to set email alerts
|

Factors associated with graft survival and endothelial cell density after Descemet’s stripping automated endothelial keratoplasty

Abstract: Postoperative endothelial cell loss leads to graft failure after corneal transplantation, and is one of the important issues for long-term prognosis. The objective of this study was to identify clinical factors affecting graft survival and postoperative endothelial cell density (ECD) after Descemet’s stripping automated endothelial keratoplasty (DSAEK). A total of 198 consecutive Japanese patients (225 eyes) who underwent DSAEK were analysed using Cox proportional hazard regression and multiple linear regressi… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

3
68
4
1

Year Published

2016
2016
2021
2021

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 68 publications
(76 citation statements)
references
References 52 publications
3
68
4
1
Order By: Relevance
“…There were eight patients with graft failure within 1 year after DSAEK (primary graft failure in four eyes, graft failure at 3 months in 2 eyes and at 6 months in 2 eyes). We defined the ECD as 300 cells/mm 2 as previously reported, 6 because the ECD could not be directly measured due to corneal edema. At 1 and 3 months, ECD measurement was difficult in some patients due to residual corneal edema or interface irregularity.…”
Section: Discussionmentioning
confidence: 99%
See 4 more Smart Citations
“…There were eight patients with graft failure within 1 year after DSAEK (primary graft failure in four eyes, graft failure at 3 months in 2 eyes and at 6 months in 2 eyes). We defined the ECD as 300 cells/mm 2 as previously reported, 6 because the ECD could not be directly measured due to corneal edema. At 1 and 3 months, ECD measurement was difficult in some patients due to residual corneal edema or interface irregularity.…”
Section: Discussionmentioning
confidence: 99%
“…From the correlation analyses, we excluded five eyes in which air injection was performed for the treatment of postoperative double chamber, because air injection is associated with the ECD loss after DSAEK. 5,6,25 To assess the differences in the time courses of decreases in postoperative ECD between the ECD ‡1200 and the ECD <1200 groups, a one-way ANOVA was used. To compare the differences in protein and cytokine levels across the groups, the Mann-Whitney U test was used.…”
Section: Discussionmentioning
confidence: 99%
See 3 more Smart Citations