IntroductionThe sustainability and rising costs of the health‐care system are of concern. Although health‐care reforms impact various areas of care, there is only limited evidence on how regulations affect home‐care agencies and health‐care delivery.ObjectivesThe primary aim was to explore different financial and regulatory mechanisms and how they drive differences in the organizational structures, processes, and work environment of home‐care agencies.Design and methodsWe used data from a national multicenter cross‐sectional study of Swiss home care that included a random sample of 88 home‐care agencies with a total of 3223 employees. Data was collected in 2021 through agency and personnel questionnaires including geographic characteristics, financial and regulatory mechanisms, service provision, financing, work environment, resources and time allocation, and personnel recruitment. We first conducted a cluster analysis to build agency groups with similar financial and regulatory mechanisms. We then performed Fisher's exact, ANOVA, and Kruskal–Wallis tests to determine group differences in organizational structures, processes, and work environments. Finally, we performed a lasso regression to determine which variables were predictive for the groups.ResultsFour agency groups were built, differing in view of financial and regulatory mechanisms and we found differences in the range and amount of services provided, with regard to employment conditions and cost structures.DiscussionThe most prominent differences were found between agency groups with versus agency groups without a service obligation. Financial incentives must be well aligned with the goal of achieving and maintaining financially sustainable, accessible, and high‐quality home care.