Factors Associated With Pathological Cardio-Ankle Vascular Index in Patients With Acute Ischemic Stroke

Сумин, А. Н.; Ott, Martin; Колмыкова, Ю. А.; Кухарева, И. Н.; Трубникова, О. А.; Коваленко, А. В.

doi:10.17802/2306-1278-2018-7-1-67-75

Cited by 2 publications

(3 citation statements)

References 13 publications

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“…Our study did not reveal a clear correlation of the START and CAVI indices with risk factors (except for age). These findings are consistent with the results of studies on CAVI assessment in patients with clinical manifestations of atherosclerosis of a different localization [3].…”

Section: Discussionsupporting

confidence: 92%

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Potential Of The Novel START Index In Assessing Arterial Stiffness In Patients With Coronary Artery Disease

Sumin,

Shcheglova,

Gorelova

et al. 2023

Russ Open Med J

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Background — Recently, a novel method for assessing arterial stiffness was developed under the name of START (STiffness of ARTeries), which, unlike the conventional stiffness parameter β, is calculated based on other physical principles. Our study aimed to investigate the possibility of using the new START index in patients with coronary artery disease (CAD). Methods — The study included 353 patients with CAD: 277 men and 76 women. Their median age was 57.0 (53.0; 64.0) years. The arterial stiffness was assessed in all subjects using VaSera VS-1000 sphygmomanometer. The novel arterial stiffness index (START) was analyzed retrospectively. We assessed the correlation of cardio-ankle vascular index (CAVI) and START index, as well as each of these indices with risk factors in the entire cohort of those examined, and also separately for men and women. Results — In examined CAD patients, the median value of the CAVI was within the borderline values (8.0-9.0) [5]: 8.3 (7.6; 9.2) on the right side and 8.3 (7.6; 9.2) on the left side. A median value of the START index was 8.3 (7.1; 9.8) on the right and 8.1 (7.0; 9.6) on the left. A strong relationship between CAVI and START was revealed in the total sample (r=0.879, p<0.001). Women exhibited a more pronounced association (r=0.982, p<0.001) than men (r=0.805, p<0.001). For the total sample, we revealed a strong dependence of the indices on age (r=0.4, p<0.001 for CAVI; r=0.36, p<0.001 for the START index). Both stiffness indices exhibited a weak but significant correlation with glomerular filtration rate (GFR) in the entire sample of study subjects (r=-0.168, p=0.003 for CAVI; r=-0.0159, p=0.004 for START). Conclusion — In patients with CAD, the START index was strongly associated with the CAVI throughout the entire cohort, albeit the correlation in women was slightly stronger than in men. Also, these indices had similar associations with clinical factors and age. Strong correlation between these indices is important for the subsequent practical application of the START index. The possibility of using START index in similar clinical situations as the CAVI requires confirmation in further studies.

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Section: Discussionsupporting

confidence: 92%

“…Such indicator would accumulate the impact of various risk factors on the cardiovascular system throughout life. Accordingly, arterial stiffness is not only an important component of vascular aging [2], but also a powerful predictor of CVD risks; and as such, it becomes an appropriate therapeutic target [1,3].…”

Section: Introductionmentioning

confidence: 99%

Potential Of The Novel START Index In Assessing Arterial Stiffness In Patients With Coronary Artery Disease

Sumin,

Shcheglova,

Gorelova

et al. 2023

Russ Open Med J

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“…в этом же исследовании сЛси с успехом использовался для оценки восстановления эластичности сосудов в ходе реабилитации у пациентов после инсульта. согласно российским исследованиям, у пациентов, перенесших ишемический инсульт и имеющих повышенный сЛси, чаще выявляются стенозы экстракраниальных артерий и сопутствующие сердечно-сосудистые патологии (сД, хроническая сердечная недостаточность, нарушение ритма) [38].…”

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Cardio-ankle vascular index (CAVI) in diagnostics, risk and severity evaluation of magistral vessels lesion in patients with cardio-vascular diseases and type 2 diabetes

Verner

Melnik

Knjazeva

2021

Terapevticheskii arkhiv

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Assesment of arterial stiffness the substantional prognostic factor for evaluating complications of cardiovascular diseases (CVD) in patients with atherosclerosis, hypertension and type 2 diabetes, may be performed using different parameters, including cardio-ankle vascular index (CAVI). The main purpose of this review is to analyze data from studies where CAVI is used to test the arterial wall stiffness in magistral vessels. CAVI measurement is non-invasive and performed by portable devices which makes it comfortable for ambulatory use in patients who come for a check-up and also in those who already are hospitalized. It does not require any special knowledge from investigator and the test lasts a couple of minutes long. CAVI does not depend on blood pressure changes and is more specific in structural changes of arterial wall assessment than brachial-ankle pulse wave velocity (baPWV). CAVI shows considerable correlation with markers of CVD like atherosclerotic plaques in vessels, diastolic disfunction of left ventricle and angina pectoris. CAVI may be used for early monitoring and assessing the lesions of target organs in patients with atherosclerosis, chronic hypertension and type 2 diabetes. Establishing CAVI as a standart parameter in assessing patients who are at risk of CVD can help to improve complications prevention, reduce mortality and prolong their lifespan.

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Factors Associated With Pathological Cardio-Ankle Vascular Index in Patients With Acute Ischemic Stroke

Cited by 2 publications

References 13 publications

Potential Of The Novel START Index In Assessing Arterial Stiffness In Patients With Coronary Artery Disease

Potential Of The Novel START Index In Assessing Arterial Stiffness In Patients With Coronary Artery Disease

Cardio-ankle vascular index (CAVI) in diagnostics, risk and severity evaluation of magistral vessels lesion in patients with cardio-vascular diseases and type 2 diabetes

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