Factors associated with poorly controlled asthma among adults in France

Vervloët, D.; Pribil, C.; Dumur, J.-P.; Godard, P.; Salmeron, S.; Serrier, P.; Koechlin, C.; Didier, A.

doi:10.1016/j.reval.2014.04.001

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…In the ATHMOS study by Vervloet and al. [ 26 ] confirm that symptoms of rhinitis were associated with uncontrolled asthma that was previously shown by Barros et al [ 52 ] Additionally, the presence of rhinitis predicted the development of asthma [ 53 ]. In our study, rhinitis was associated with controlled asthma.…”

Section: Discussionsupporting

confidence: 66%

“…Cazzoletti et al [ 24 ] reported in their European study on asthma control that the rate of uncontrolled patients ranged from 20% (Iceland) to 67% (Italy).Almost two-third of asthmatic patients included in a study evaluating the degree of asthma control in Spain in 2006 were poorly controlled [ 25 ]. More recently, Vervloet et al found a high rate of asthmatic patients with inadequate control of asthma in real life despite the fact that 95% of patients were treated with anti-asthmatics [ 26 ]. Our study revealsed that 29% of patients had uncontrolled asthma.…”

Section: Discussionmentioning

confidence: 99%

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Factors associated with asthma control: MOSAR study (Multicenter Observational Study of Asthma in Rabat-Morocco)

et al. 2018

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BackgroundThe purpose of the study is to describe the profile of patients with asthma and to identify the signifiant risks and the protective factors associated with asthma control.MethodsA prospective epidemiological study was conducted in three hospitals of Rabat-Morocco and included 396 patients with asthma. Differences in characteristics across the levels of asthma control were compared by the one-way analysis of variance for continuous variables, and chi-square test was used for categorical variables. The risk and protective factors associated with the asthma control levels were determined by Proportional Odds Model (POM) for bivariate and multivariate ordinal logistic regression, also expressed as Odds Ratios (OR) and 95% Confidence Intervals (95% CI).ResultsFrom 7440 patients screened by 28 physicians, 396 were included in study. 53% of the particiants sufferd controlled, 18% had partly controlled and 29% had uncontrolled asthma symptoms. A multivariate ordinal logistic regression analysis showed that having respiratory infections (AOR = 5.71), suffering from concomitant diseases (AOR = 3.36) and being allergic to animals (AOR = 2.76) were positively associated with poor control of asthma. However, adherence to treatement (AOR = 0.07), possession of health insurance (AOR = 0.41) and having more than 2 children (AOR = 0.47) were associated with good asthma control.ConclusionThe study established a clinical-epidemiological profile of asthmatic patients in Rabat region in Morocco. By ordinal logistic regression we found that 6 factors - respiratory infections, concomitant diseases, animals allergy, adherence to treatment, health insurance and having more than two children – were associated with asthma control.

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Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Factors associated with asthma control: MOSAR study (Multicenter Observational Study of Asthma in Rabat-Morocco)

et al. 2018

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“…A total of 16 studies examined relationships between reduction in unscheduled care and ACT score improvement from "not well controlled" to "well-controlled" asthma [47,49,51,[53][54][55][67][68][69][70][71][72][73][74][75][76]. Statistically significant results were reported for unscheduled outpatient clinic visits by two studies [54,74], for emergency department visits by five studies [54,55,71,74,75], for hospitalizations by three studies [55,71,72], for 'urgent health care utilization' by one study [69] and use of inhaled corticosteroids by one study [67].…”

Section: Act Score and Resource Use And Costsmentioning

confidence: 99%

Relationship between the Asthma Control Test (ACT) and other outcomes: a targeted literature review

et al. 2020

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Background: The Asthma Control Test (ACT) has been used to assess asthma control in both clinical trials and clinical practice. However, the relationships between ACT score and other measures of asthma impact are not fully understood. Here, we evaluate how ACT scores relate to other clinical, patient-reported, or economic asthma outcomes. Methods: A targeted literature search of online databases and conference abstracts was performed. Data were extracted from articles reporting ACT score alongside one or more of: Asthma Control Questionnaire (ACQ) score; rescue medication use; exacerbations; lung function; health−/asthma-related quality of life (QoL); sleep quality; work and productivity; and healthcare resource use (HRU) and costs. Results: A total of 1653 publications were identified, 74 of which were included in the final analysis. Of these, 69 studies found that improvement in ACT score was related to improvement in outcome(s), either as correlation or by association. The level of evidence for each relationship differed widely between outcomes: substantial evidence was identified for relationships between ACT score and ACQ score, lung function, and asthma-related QoL; moderate evidence was obtained for relationships between ACT score and rescue medication use, exacerbations, sleep quality, and work and productivity; limited evidence was identified for relationships between ACT score and general health-related QoL, HRU, and healthcare costs. Conclusions: Findings of this review suggest that the ACT is an appropriate measure for overall asthma impact and support its use in clinical trial settings. GlaxoSmithKline plc. study number HO-17-18170.

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