Factors associated with potentially inappropriate medication use in elderly Koreans in an outpatient setting: a population‐based study

Factors associated with potentially harmful drug–drug interactions in older Korean people: A population‐based study

“…The prevalences of all three were higher in women who were medical aid beneficiaries, visited multiple healthcare centers during the year, visited healthcare centers as outpatients frequently during the year and who were co‐prescribed six or more drugs in a single prescription. Previous studies investigating inappropriate medication use of older adults in Korea suggested that similar factors are associated with prescription of inappropriate medication . These findings suggest that healthcare providers should pay extra attention to preventing any PHDI in older adults who share these common factors.…”

“…Previous studies investigating inappropriate medication use of older adults in Korea suggested that similar factors are associated with prescription of inappropriate medication. 8,9 These findings suggest that healthcare providers should pay extra attention to preventing any PHDI in older adults who share these common factors. That is, it is necessary to meticulously examine current medications to prevent such interactions with newly prescribed drugs.…”

“…A cohort study carried out in Brazil showed that inappropriate drug use in older adults increased the mortality rate by 44% . Similarly, 70–80% of older adults were found to use inappropriate drugs in Korea …”

“…7 Similarly, 70-80% of older adults were found to use inappropriate drugs in Korea. 8,9 Prescription guidelines have been tightened as a countermeasure to reduce the errors in prescribing medications to older adults. 10 The Beers Criteria recommended by the American Geriatrics Society are among the most widely used guidelines for prescribing medications in older adults.…”

Impact of a nationwide prospective drug utilization review program to improve prescribing safety of potentially inappropriate medications in older adults: An interrupted time series with segmented regression analysis

“…12 The proportion of older adults prescribed PIMs was reported to be 31% to 57% in the United States, 13,14 24% to 54% in Europe, 15,16 and as high as 70% to 86% in Asian. 17,18 PIM has serious implications in longterm care facilities, and the prevalence of PIM defined using the Beers criteria reached 18.5% to 82.6% in a systematic review. 19 In a metaanalysis of 33 studies, PIMs significantly increased the risk of ADRs and hospitalization, 20 and another meta-analysis found an increased risk of death in older adults who were first prescribed PIMs.…”