This study sought to identify the challenges that lecturers and students faced in developing English language communicative competence for academic purposes at a university within the College of Humanities situated in Zliten city in the north of Libya. This research canvassed students’ and lecturers’ experiences and perceptions in the teaching and learning of academic English in a foreign language context. Within a case study approach, a convergent mixed methods research design was used. Data was collected through qualitative and quantitative methods in an interpretative paradigm. The study employed three data generation methods, a semi-structured interview, focus group discussion, and questionnaires. The findings suggest that the qualitative and quantitative findings in this study can be classified into four categories of EFL Libyan learning challenges namely: linguistic, cultural, institutional, and structural challenges. Linguistic challenges are those related to language issues confronted by both lecturers and students. Most participants (lecturers and students) agreed that Arabic and English are linguistically dissimilar. They are unable to comprehend academic literature in the English language because of the phonological differences between Arabic and English. It is considered the most common linguistic challenge with respect to student anxiety and inadequacy regarding the attainment of academic English proficiency. The cultural challenge manifests as a dissonance between students’ cultural predilections and the decoding required for meaning making in English as a foreign language. A cultural insistence and expectation for Arabic hegemonic communication exacerbates the development of communicative competence in the target language. Institutional challenges are described as the general position of higher education in Libya, and the problems students encounter when joining this education system. The effect of insular politics also negatively impacts effective institutional operations. Finally, structural challenges were related to the overall teaching program coherence. This included the lack of appropriate curriculum design standards and poorly designed policies of English language teaching and learning. The study concludes by making suggestions to improve communicative competence in the target language at the research site.