Factors Related to the Occurrence of Typical Paroxysmal Abnormalities in the EEG Records of Epileptic Patients

Abstract

This diagnosis was based on characteristic history, occurrence of several convulsive o r other paroxysmal seizure episodes reported by qualified observers, pertinent data on medical record and, in many instances, direct observation of patients during ictal episodes by members of the EEG Laboratory. Epilepsia, 1970,ll: 361-381 RESULTS General findingsOn the basis of the criteria described above the patients were subdivided into three main groups: (1) with all positive records, (2) with all negative records and (3) with * Epileptiform activity includes all forms of paroxysmal discharges (spikes, sharp waves, spike-wave complexes, prolonged runs of paroxysmal rhythms as seen in electrographic seizures), both focal and generalized. Records were considered "positive" only if such type of activity was present. Both records with non-paroxysmal abnormalities and borderline or normal records were considered "negative" for the purpose of this study (see DISCUSSION).Epilepsiu, 1970, 11: 361-381

Sensitivity and Specificity of Electroencephalography (EEG) Among Patients Referred to an Electrophysiology Lab in Bangladesh

“…Granieri et al 49 , Olafsson et al 51 and Tekle-Haimanot et al 53 found a higher proportion of HTCS like our study. Studies on adult epilepsies showed that the chance of detecting interictal epileptiform discharges (IEDs) from the first EEG varies between 29% and 55% [54][55][56] . A Repeat EEG may ultimately demonstrated the IEDs in 80%-90% of the patients 54,56 .…”

“…Studies on adult epilepsies showed that the chance of detecting interictal epileptiform discharges (IEDs) from the first EEG varies between 29% and 55% [54][55][56] . A Repeat EEG may ultimately demonstrated the IEDs in 80%-90% of the patients 54,56 . We had a similar yield of abnormal report in EEG.…”

Variations in EEG discharges predict ADHD severity within individual Smith-Lemli-Opitz patients

“…In particular, incomplete sets of EEG data may have resulted in a type II error associated with misclassification of subjects as no-IED when the missing EEGs would have shown IEDs; however, this possibility is mollified somewhat by the fact that 3 EEGs have been shown to be .80% sensitive for sharp waves in individuals who have them. 16,17 Results of behavioral measures could potentially be influenced by unreliable parent informants, although it is not expected that such bias would preferentially affect a single group. Clinician and tester bias was reduced through blinding, as IED group status was not determined until after testing was complete.…”

“…The rationale for this grouping scheme is based on previous studies demonstrating that, in individuals with epilepsy, a single EEG is typically specific but not sensitive for IEDs, while the recording of 3 or more EEGs improves sensitivity to .80%. 16,17 Only one participant (S21) in our study had a documented history of epilepsy and antiepileptic drug (AED) treatment; oxcarbazepine (not a known spike suppressor) was initiated between the 6-and 12-month visits. Other notable histories included a questionable history of a single seizure in the remote past (S12), and teacher-reported "staring spells" (S15); neither child was diagnosed with epilepsy.…”

Sleep-Wake Cycle Rhythm of the Seizures and Correlation with Clinic and Neuroimaging Findings

“…anor mal lik tes pit edi lir ken, [15][16][17][18] tek rar la nan ka yıt -lar da bu oranın %80-90'a çık tı ğı gös te ril miş tir. 15,16 Uy ku dep ri vas yo nu EEG ka yıt la ma la rın da ise fark lı ça lış ma lar da, ça lış ma di zay nı ve po pü lasyon da ki far lı lık lar doğ rul tu sun da, in te rik tal epilep ti form ak ti vas yon ora nı %32-69.4 ara sın da de ğiş ti ği sap tan mış tır.…”