“…These findings support the notion that frailty is not strictly related to biological age and that the number of comorbidities does not fully correlate with their severity (Afilalo et al, 2012;Farhat et al, 2012;Fernández-Garrido et al, 2014a;Fried et al, 2004;Partridge et al, 2012;Robinson et al, 2013) As the frailty burden increases, the occurrence of one or more complications are more likely. Robinson et al (2013) reported that infection was the most common complication in both surgical groups, and perhaps related to this, a decrease in immune function has also been described in frail individuals (Furlan et al, 2013;Heffernan et al, 2012;Leng et al, 2009;Reddan et al, 2003). Length of hospital stay increased as the frailty burden accumulated, and thus these patients also accrued higher economic and health-professional costs during this postsurgical period (Cohen et al, 2012;Lasithiotakis et al, 2013;Lee et al, 2010;Makary et al, 2010;Robinson et al, 2013).…”