Background : Speech disorders are one of the problems that are often found in children. According to the National Center for Health Statistics (NCHS), based on parents' reports (outside of hearing loss and cleft palate), the incidence of disorders is 0.9% in children under the age of 5 years, and 1.94% at the age of 5- For 14 years, the need for managing disorders of children's verbal communication can be done with a variety of therapies, one of which is Murottal Al-Qur'an therapy. Murottal Al-Qur’an provides sound effect received by the ear and system and then transmitted to all organs of the body. Sound affects the cells of the body that have their own vibrations and cause the cells of the body to rearrange the articles in it. Where the role here is the vagus nerve which helps regulate heart rate, respiration, speech, brings motor sensory impulses to larynx of the heart and diaphragm so that the sound effects on autistic children can improve children’s communication skills. The method used in this research is Experimental Quasy with pre and post without control research design. Sampling using purposive sampling technique, in getting 10 respondents in accordance with inclusion criteria, data collection was done by using questionnaires and observation sheets, namely by using the DDST sheet (Denver Development Screening Test). Observations were made before and after Murottal Al-Qur'an therapy. The collected data is then processed using the Marginal Homogenity Test P value is obtained on the DDST (Denver Development Screening Test) sheet after the Murottal Al-Qur'an therapy is 0.001. The conclusion in this study is that Murottal Al-Qur'an therapy has an effect on verbal communication of children aged 3-5 years in the SaQu (Sahabat Qur'ani) TAUD of Polewali Mandar Regency.