Falcons From the United Arab Emirates Infected With Chlamydia psittaci/C abortus Intermediates Specified as Chlamydia buteonis by Polymerase Chain Reaction

Stalder, Sandro; Marti, H. R.; Borel, Nicole; Vogler, Barbara Renate; Pesch, Theresa; Prähauser, Barbara; Wencel, Peter; Laroucau, Karine; Albini, Sarah

doi:10.1647/20-00050

Cited by 6 publications

(5 citation statements)

References 40 publications

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“…It is plausible that these global lineages also include other avian C. abortus/C. psittaci intermediates, which have presently not been whole-genome sequenced or multi-locus sequence typed [1,35,[38][39][40].…”

Section: Discussionmentioning

confidence: 99%

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Draft genomes of novel avian Chlamydia abortus strains from Australian Torresian crows (Corvus orru) shed light on possible reservoir hosts and evolutionary pathways

Kasimov,

White,

Jelocnik

2023

Microbial Genomics

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Chlamydia abortus, an obligate intracellular bacterium, is a major causative agent of reproductive loss in ruminants, with zoonotic potential. Though this pathogen is primarily known to infect livestock, recent studies have detected and isolated genetically distinct avian strains of C. abortus from wild birds globally. Before this study, only five avian C. abortus genomes were publicly available. Therefore, we performed culture-independent probe-based whole-genome sequencing on clinical swabs positive for avian C. abortus obtained from Australian Torresian crows (Corvus orru) in 2019 and 2020. We successfully obtained draft genomes for three avian C. abortus strains (C1, C2 and C3), each comprising draft chromosomes with lengths of 1 115 667, 1 120 231 and 1 082 115 bp, and associated 7 553 bp plasmids, with a genome completeness exceeding 92 %. Molecular characterization revealed that these three strains comprise a novel sequence type (ST333), whilst phylogenetic analyses placed all three strains in a cluster with other avian C. abortus genomes. Interestingly, these three strains share a distant genomic relation (2693 single nucleotide variants) with the reference strain 15-58d/44 (ST152), isolated from a Eurasian magpie (Pica pica) in Poland, highlighting the need for more publicly available genomes. Broad comparative analyses with other avian C. abortus genomes revealed that the three draft genomes contain conserved Chlamydia genomic features, including genes coding for type III secretion system and polymorphic membrane proteins, and potential virulence factors such as the large chlamydial cytotoxin, warranting further studies. This research provides the first avian C. abortus draft genomes from Australian birds, highlighting Torresian crows as novel reservoir hosts for these potential pathogens, and demonstrates a practical methodology for sequencing novel Chlamydia genomes without relying on traditional cell culture.

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Section: Discussionmentioning

confidence: 99%

“…abortus / C. psittaci intermediates, which have presently not been whole-genome sequenced or multi-locus sequence typed [1, 35, 38–40].…”

Section: Discussionmentioning

confidence: 99%

Draft genomes of novel avian Chlamydia abortus strains from Australian Torresian crows (Corvus orru) shed light on possible reservoir hosts and evolutionary pathways

Kasimov,

White,

Jelocnik

2023

Microbial Genomics

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“…Despite Chlamydia psittaci being previously found in these animals, diseases related to this agent are not often reported [ 36 , 49 , 50 ]. However, the transmission of this agent to humans can occur through exposition to domestic, pet, and wild birds [ 51 , 52 , 53 ].…”

Section: Bacteria Found In Captive Birds Of Preymentioning

confidence: 99%

Antimicrobial Resistance and Virulence Potential of Bacterial Species from Captive Birds of Prey—Consequences of Falconry for Public Health

Magalhães,

Tavares,

Oliveira

2024

Animals

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Falconry has been practiced for thousands of years and is nowadays frequently employed in activities such as pest control, hunting, falcon racing, and environmental education. Antimicrobial resistance levels have risen in the past years, constituting an emerging global problem with a direct impact on public health. Besides both topics being studied on their own, information on the role of captive birds of prey in the potential dissemination of virulence factors and antimicrobial resistance determinants of bacterial origin is scarce. Multidrug-resistant bacteria, including some extended-spectrum β-lactamase producers, have already been found in several captive birds of prey. Most of the virulence factors found in captive raptors’ bacteria were related to adherence and invasion abilities, toxin production, and flagella. These birds may acquire these bacteria through contaminated raw food and the exchange of animals between keepers and zoological facilities. More studies are required to confirm the role of captive birds of prey in disseminating resistant bacteria and on the routes of interaction between synanthropic species and humans.

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“…8 Früher als «atypisch» oder «intermediär» bezeichnet, verursachen C. avium, C. gallinacea, C. buteonis und Candidatus C. ibidis keine oder nur milde klinische Anzeichen in den betroffenen Vogelarten und zoonotische Infektionen wurden bis dato noch nicht schlüssig nachgewiesen. 78 Einige der nicht-C. psittaci-Chlamydienspezies scheinen bevorzugt in gewissen Vogelarten aufzutreten, zum Beispiel C. buteonis in Bussarden und Falken 52,92 oder C. gallinacea in verschiedenen Hühnervögeln. 80 Bei Geflügelhaltern in Italien konnte C. gallinacea-DNA in respiratorischen Proben nachgewiesen werden, alle Tiere und Menschen waren vor oder während der Probennahme symptomfrei.…”

Section: Weitere Aviäre Chlamydienunclassified

“…psittaci/ C. abortus intermediäre Spezies» gefunden, 93 die vermutlich noch nicht genauer charakterisierte neue Chlamydienspezies darstellen, ähnlich wie die relativ neue Spezies C. buteonis, die zuvor als eine solche intermediäre Spezies bezeichnet wurde. 92 Seit neustem wurden auch aviäre C. abortus Stämme beschrieben, die sich nur wenig von den Wiederkäuerstämmen unterscheiden. 58,99 Weitere Chlamydien bei (Haus-)Säugetieren 78 C. suis ist in der Schweizer Mastschweinepopulation weit verbreitet, kommt meistens ohne klinische Anzeichen im Darm vor und wird mit dem Kot ausgeschieden.…”

Section: Weitere Aviäre Chlamydienunclassified

Update on the zoonotic potential of Chlamydia

Albini¹,

Marti²,

Imkamp³

et al. 2023

SAT

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Knowledge of the obligate intracellular bacteria from the Chlamydiaceae family has increased significantly in recent years. Not only new chlamydia species, such as Chlamydia avium or C. buteonis in birds have been described, but also known chlamydia in new host species, such as C. psittaci in horses. This review article provides an up-to-date overview of the zoonotic potential of C. psittaci, C. abortus, C. caviae and C. felis and summarizes current findings on other chlamydia species in different animal species; supplemented by information on optimal sampling and pathogen detection.

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Falcons From the United Arab Emirates Infected With Chlamydia psittaci/C abortus Intermediates Specified as Chlamydia buteonis by Polymerase Chain Reaction

Cited by 6 publications

References 40 publications

Draft genomes of novel avian Chlamydia abortus strains from Australian Torresian crows (Corvus orru) shed light on possible reservoir hosts and evolutionary pathways

Draft genomes of novel avian Chlamydia abortus strains from Australian Torresian crows (Corvus orru) shed light on possible reservoir hosts and evolutionary pathways

Antimicrobial Resistance and Virulence Potential of Bacterial Species from Captive Birds of Prey—Consequences of Falconry for Public Health

Update on the zoonotic potential of Chlamydia

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