Familial Kyrle's disease: a case report

Shivakumar, V; Okade, Rajendra; Rajkumar, V; Prathima, K. M.

doi:10.1111/j.1365-4632.2007.03299.x

Cited by 11 publications

(6 citation statements)

References 6 publications

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“…The etiology of the disease remains unknown but several hypotheses were proposed such as defective differentiation of the epidermis and the dermal-epidermal junction secondary to glycosylation processes [9], infectious etiology, probably anaerobic bacteria [10] and genetic etiology [11,12].…”

Section: Discussionmentioning

confidence: 99%

Kyrle’s Disease in a Patient with Delusions of Parasitosis

Tampa

Sârbu

Matei

et al. 2016

Romanian Journal of Internal Medicine

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Acquired perforating disorders are a group of uncommon skin conditions characterized by transepidermal extrusion of altered dermal material, most often associated with diabetes mellitus and chronic kidney failure. Delusional parasitosis is a primary psychiatric disorder in which affected patients have fixed, false beliefs that their skin is infested by parasites, in the absence of any evidence supporting their statements.A 69 year old malepatient addressed the Dermatology Department for a skin eruption consisting of multiple umbilicated keratotic papules with a generalized distribution. The patient believed that the lesions were produced by small parasites entering and exiting his skin. The histopathological examination confirmed the clinical diagnosis of Kyrle's disease. The psychiatric examination established the diagnosis of delusions of parasitosis. This is the first reported case of Kyrle's disease associated with delusions of parasitosis. There is no evidence supporting the hypothesis that delusions of parasitosis might be a predisposing factor for Kyrle's disease. However, we believe that the pruritic dermatosis might have triggered the delusions of parasitosis due to the associated pruritus. On the other hand the constant excoriations and traumatizing of a skin prone to develop idiopathic Kyrle's disease in the attempt to remove the parasites prevented the complete resolution of the lesions.

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Section: Discussionmentioning

confidence: 99%

Kyrle’s Disease in a Patient with Delusions of Parasitosis

Tampa

Sârbu

Matei

et al. 2016

Romanian Journal of Internal Medicine

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“…It is characterized by hyperkeratotic papules and nodules, with a central keratotic plug most commonly on the lower extremities with marked disposition for calf, tibial region and posterior aspect. [ 3 ] Arms, head and neck region are also involved while palms and soles are involved rarely. Koebner phenomenon has been noted in some cases like in our case.…”

Section: Discussionmentioning

confidence: 99%

“…Along with diabetes mellitus and chronic renal failure, it is also seen with tuberculosis, pulmonary aspergillosis, scabies, atopic dermatitis, AIDS, neurodermatitis, malignancy, hepatic disorders, congestive heart failure and endocrinological disorders. [ 3 11 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] It is commonly seen in patients with diabetes, renal disease and rarely in liver disease. [ 2 ] KD is regarded as a genetically determined disease with onset during adulthood usually between the age of 30 and 50 years but onset as early as age 5 years and as late as 75 years has been reported with[ 3 ] female-to-male ratio of up to 6:1. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

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Kyrle′s disease in a patient of diabetes mellitus and chronic renal failure on dialysis

Nair

Jivani

Diwan

2015

J Family Med Prim Care

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Kyrle's disease (KD) is an acquired perforating dermatosis associated with an underlying disorder such as diabetes mellitus or chronic renal failure. It presents as multiple discrete, eruptive papules with a central crust or plug, often on the lower extremities. A keratotic plug is seen histologically in an atrophic epidermis and may penetrate the papillary dermis with transepidermal elimination of keratotic debris without collagen or elastic fibers. Various therapies have been reported that include cryotherapy, laser therapy, narrow-band ultraviolet B and use of topical or systemic retinoids. Hereby a case of 64-year-old male, a known case of diabetes mellitus, hypertension and chronic renal failure who developed KD is presented.

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“…водят описание семейных случаев болезни [4,5], сведения о возможном участии инфекционного агента в качестве триггерного фактора [6]. указывается на взаимосвязь заболевания с нарушением метаболизма витамина А, с васкулопатией, хронической почечной недостаточностью, сахарным диабетом, заболеваниями печени и селезенки, застойной сердечной недостаточностью, гиперлипидемией, гипотиреозом [6][7][8][9][10][11][12][13].…”

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A rare case study of a female patient suffering from Kyrle disease (hyperkeratosis follicularis etparafollicularis in cutem penetrans)

Voytsekhovskaya¹,

Lvov²,

Катунина³

et al. 2011

Vestnik dermatologii i venerologii

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The article presents a literature review and case study of a rare form of dermatitis in a female patient aged 61 - Kyrle disease (hyperkeratosis follicularis et parafollicularis in cutem penetrans). It also provides a detailed description of the clinical picture and differential diagnostics of the disease. The following typical changes were observed based on the results of histological examination: epidermic invaginations filled with corneous masses and areas of focal parakeratosis. Essential improvement in skin process dynamics was achieved against the background of treatment with Acitretin.

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Familial Kyrle's disease: a case report

Cited by 11 publications

References 6 publications

Kyrle’s Disease in a Patient with Delusions of Parasitosis

Kyrle’s Disease in a Patient with Delusions of Parasitosis

Kyrle′s disease in a patient of diabetes mellitus and chronic renal failure on dialysis

A rare case study of a female patient suffering from Kyrle disease (hyperkeratosis follicularis etparafollicularis in cutem penetrans)

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