Familial Polyposis in Children: Early Detection and Preferred Treatment

Pl, Leggett; Rm, Arensman; Kw, Falterman

doi:10.1097/00007611-198404000-00013

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1987

1993

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Cited by 3 publications

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“…The condition is characterized by multiple adenomatous polyps, primarily in the colon and less frequently in the small intestine and stomach. It usually presents after puberty although it has been described in younger children (5). The greatest concern is the eventual development of colon cancer inunoperated patients.…”

Section: Discussionmentioning

confidence: 99%

Sulindac‐Induced Regression of Adenomatous Colonic Polyps in a Child with a History of Hepatoblastoma

Schussheim,

Gold,

Levine

1993

J. pediatr. gastroenterol. nutr.

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Section: Discussionmentioning

confidence: 99%

Sulindac‐Induced Regression of Adenomatous Colonic Polyps in a Child with a History of Hepatoblastoma

Schussheim,

Gold,

Levine

1993

J. pediatr. gastroenterol. nutr.

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Surgical alternatives in the treatment of polyposis coli

Welling

Beart

1987

Seminars in Surgical Oncology

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Surveillance in relatives of patients with adenomatous polyposis

Berk

Cohen

McLeod

et al. 1987

Seminars in Surgical Oncology

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Registry ascertainment of kindreds with adenomatous polyposis (AP) reduces the incidence of colorectal carcinoma by medical monitoring for offspring and siblings of affected patients. Due to its pleiomorphic genotype and a 50% risk for AP in each patient's progeny, early screening is mandatory. Flexible sigmoidoscopy, averaging from puberty to age 48, annually or every two years, is one diagnostic technique that does not result in excess patient discomfort or cost. Timely examination is facilitated when eye anomalies, osteomas, or epidermoid cysts are present in childhood as potential clinical markers for AP. Denial, misperceptions, and fear may impede surveillance in the absence of education by the registry health care team.

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Familial Polyposis in Children: Early Detection and Preferred Treatment

Cited by 3 publications

References 0 publications

Sulindac‐Induced Regression of Adenomatous Colonic Polyps in a Child with a History of Hepatoblastoma

Sulindac‐Induced Regression of Adenomatous Colonic Polyps in a Child with a History of Hepatoblastoma

Surgical alternatives in the treatment of polyposis coli

Surveillance in relatives of patients with adenomatous polyposis

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