Background: 2007 marks the 20th anniversary of the first successful laparoscopic cholecystectomy. Exactly two decades down the road now, laparoscopic surgery has evolved from a limited innovation to a routine surgical tool used to treat virtually all surgical indications. To commemorate this landmark historical event, we set out to collate all published literature to compile an archive encompassing all the techniques and their variations described for port-site closure -an integral part of essentially every laparoscopic operation. Methods/Results: A Medline search in conjunction with diligent cross-referencing of the index articles retrieved a total of 39 relevant publications. The array of differing techniques of various sophistications and their myriad modifications are systematically categorized into external hand-sutured techniques (15) and laparoscopic-assisted techniques (25). The latter constitutes the main bulk of the work and is further subdivided into methods making use of: (i) specially designed complex devices; (ii) suture carrier; (iii) straight needle; and (iv) needle/angiocatheter as conduit. They are critically appraised in terms of ergonomics, security and cost-effectiveness. Conclusion: Publications dedicated to perfection of the closure technique have proliferated and improvements are continuously being made. Practising surgeons should be cognisant of the full range of techniques while familiarizing themselves with the useful ones deemed simple, safe and effective.