Fast Colorimetric Method for the Detection of Captagon Based on a General Sensor Design Involving Aptamers and Gold Nanoparticles

Alfadly, Abbas; Abdulwahid, Ali Abdulrazzaq; Saleh, Afrodet A.

doi:10.5101/nbe.v12i2.p124-131

Cited by 2 publications

(1 citation statement)

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“…In particular, there is an increasing demand for rapid, convenient, and high precision medical diagnosis techniques for detecting coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome (SARS), and other highly contagious infectious diseases (Alfadly et al, 2020;Chu et al, 2021;X. Dong et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Magnetic frequency mixing technological advances for the practical improvement of point‐of‐care testing

Wang

Zheng

et al. 2021

Biotech & Bioengineering

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Nanomaterials, especially superparamagnetic nanomaterials, have recently played essential roles in point-of-care testing due to their intrinsic magnetic, electrochemical, and optical properties. The inherent superparamagnetism of magnetic nanoparticles makes them highly sensitive for quantitative detection. Among the various magnetic detection technologies, frequency mixing technology (FMT) technology is an emerging detection technique in the nanomedical field. FMT sensors have high potential for development in the field of biomedical quantitative detection due to their simple structure, and they are not limited to the materials used. In particular, they can be applied for large-scale disease screening, early tumor marker detection, and low-dose drug detection. This review summarizes the principles of FMT and recent advances in the fields of immunoadsorption, lateral flow assay detection, magnetic imaging, and magnetic nanoparticles recognition. The advantages and limitations of FMT sensors for robust, ultrasensitive biosensing are highlighted. Finally, the future requirements and challenges in the development of this technology are described. This review provides further insights for researchers to inspire the future development of FMT by integration into biosensing and devices with a broad field of applications in analytical sensing and clinical usage.frequency mixing technology (FMT), lateral flow assay (LFA), magnetic imaging, magnetic nanoparticles (MNPs), point-of-care testing (POCT) | INTRODUCTIONRapid medical diagnosis is difficult using current laboratory testing techniques and their application is hindered by factors such as equipment requirements, operator capabilities, and the testing time.In particular, there is an increasing demand for rapid, convenient, and high precision medical diagnosis techniques for detecting coronavirus disease 2019 (COVID-19), severe acute respiratory syndrome (SARS), and other highly contagious infectious diseases (Alfadly et al., 2020;Chu et al., 2021;X. Dong et al., 2021). Point-of-care testing (POCT) can be used for in vitro clinical testing and diagnosis (Wei et al., 2021;Yan et al., 2019). POCT usually refers to detection techniques that do not require a professional operator to perform tests at the bedside next to the patient (Nichols, 2003;Wang et al., 2021;Xia et al., 2016). POCT is characterized by rapid analysis at the sampling site, and thus complicated laboratory processing procedures are not required (Sharma et al., 2021). POCT methods might not have the same level of sensitivity and accuracy compared with laboratory-level medical diagnosis techniques. However, with the advantages of its simple implementation and lack of requirement for professional operational support, this technology receives widespread attention in countries and regions, especially those with a low level of

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Section: Introductionmentioning

confidence: 99%