Fast Detection of Myricetin With the Use of Dedicated Microdroplets

Xiong, Zuoren; Zhang, Hai; Lu, Yijun; Zhang, Lingli; Sun, Weimin; Liu, Yongjun

doi:10.1109/jsen.2019.2945044

Cited by 8 publications

(3 citation statements)

References 30 publications

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“…Recently, LC droplets have been extensively investigated. Due to the enormous surface-to-volume ratio and the fact that tiny changes in the surface anchoring energy can result in signal amplification and achieve a lower LOD, LC droplets have distinct advantages in the field of highly sensitive biosensors [ 103 ]. Typically, LC droplets can be fabricated via the stirring emulsification, the ultrasonication emulsification, the membrane emulsification, and the microfluidic encapsulation.…”

Section: Geometries Of Lcs In Biosensingmentioning

confidence: 99%

Liquid Crystal Biosensors: Principles, Structure and Applications

Wang

et al. 2022

Biosensors

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Liquid crystals (LCs) have been widely used as sensitive elements to construct LC biosensors based on the principle that specific bonding events between biomolecules can affect the orientation of LC molecules. On the basis of the sensing interface of LC molecules, LC biosensors can be classified into three types: LC–solid interface sensing platforms, LC–aqueous interface sensing platforms, and LC–droplet interface sensing platforms. In addition, as a signal amplification method, the combination of LCs and whispering gallery mode (WGM) optical microcavities can provide higher detection sensitivity due to the extremely high quality factor and the small mode volume of the WGM optical microcavity, which enhances the interaction between the light field and biotargets. In this review, we present an overview of the basic principles, the structure, and the applications of LC biosensors. We discuss the important properties of LC and the principle of LC biosensors. The different geometries of LCs in the biosensing systems as well as their applications in the biological detection are then described. The fabrication and the application of the LC-based WGM microcavity optofluidic sensor in the biological detection are also introduced. Finally, challenges and potential research opportunities in the development of LC-based biosensors are discussed.

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Section: Geometries Of Lcs In Biosensingmentioning

confidence: 99%

Liquid Crystal Biosensors: Principles, Structure and Applications

Wang

et al. 2022

Biosensors

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“…The rapid dosage configuration of MY is crucial for its application in a variety of therapeutic therapies for different malignancies [ 163 , 164 ]. Detection of MY has been suggested and demonstrated using a 5CB droplet-based sensing technique by Xiong et al [ 165 ]. It was created using a syringe pump attached to a tapered capillary microtube, and it was functionalized in the aqueous phase using DTAB and DNA.…”

Section: Overview Of Lc Droplet-based Biosensors For Poc Diagnosis Of...mentioning

confidence: 99%

Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing

Xie

et al. 2022

Biosensors

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The development of biosensing platforms has been impressively accelerated by advancements in liquid crystal (LC) technology. High response rate, easy operation, and good stability of the LC droplet-based biosensors are all benefits of the long-range order of LC molecules. Bioprobes emerged when LC droplets were combined with biotechnology, and these bioprobes are used extensively for disease diagnosis, food safety, and environmental monitoring. The LC droplet biosensors have high sensitivity and excellent selectivity, making them an attractive tool for the label-free, economical, and real-time detection of different targets. Portable devices work well as the accessory kits for LC droplet-based biosensors to make them easier to use by anyone for on-site monitoring of targets. Herein, we offer a review of the latest developments in the design of LC droplet-based biosensors for qualitative target monitoring and quantitative target analysis.

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“…This unique soft photonic crystal material can be easily prepared and constructed into multidimensional structures from planar to spherical periodic structures. [18][19][20][21][22][23] By combining CLCs with fluorescent dyes, dualstate fluorescent labels can be achieved using the structural color of CLCs and the fluorescent color of fluorescent dyes. Qin et al proposed a dual-tone ink process that injects fluorescence into CLCs by doping with a newly synthesized fluorescent molecule DC5 that emits cyan fluorescence.…”

Section: Introductionmentioning

confidence: 99%