Fast Determination of Melanin based on Skin Hyperspectral Reflectance

Striae are common dermal lesions associated with physiological and psychological alterations, affecting the quality of life. This proposed randomized controlled trial protocol will evaluate the clinical efficacy and treatment safety of fractional CO2 laser versus fractional radiofrequency (FRF) in clinical trials. We will randomly allocate 60 subjects who present abdominal striae into two different groups for the treatment, which will be performed once a month for a 3-month period. The results will be assessed by quartile scoring criteria; by comparing digital photos taken before and after each treatment; and also, by the measurement of cutaneous temperature, skin pH, and elasticity before and after the treatment. This paper describes the rationale and the design of the randomized controlled trial, which may provide evidence for clinical application of the methodology and the quality related to the efficacy and safety of fractional CO2 laser versus the FRF protocol for striae treatment.

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“… Hyperspectral skin image in the visible light range. This image was designed based on the literature [ 30 ]. …”

Section: Figurementioning

confidence: 99%

Fractional CO2 Laser versus Fractional Radiofrequency for Skin Striae Treatment: Study Protocol for a Randomized Controlled Trial

Mendes

Alves

Barros³

et al. 2022

Healthcare

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“…Tsai et al (16) have shown that HSI technique is able to detect the differences in skin reflectance according to race, gender and body site, across the visible and near-infrared regions. More recently, Li et al (17) proposed a method for the fast determination of skin melanin based on hyperspectral reflectance and neural network with promising results. Although these studies have demonstrated the role that HSI could play as a noninvasive technique for assessing skin melanin content, there is still a need for improvements in measurement accuracy as well as in HSI image analysis algorithms to aid in better quantification of skin melanin in normal or pathological conditions.…”

Section: Introductionmentioning

confidence: 99%

Mapping the Distribution of Melanin Concentration in Different Fitzpatrick Skin Types Using Hyperspectral Imaging Technique

Manea

Savastru

Parasca

2022

Photochem & Photobiology

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Measuring skin melanin concentration in order to assess skin phototype according to Fitzpatrick's classification is a constant research goal. In this study, a new approach for assessing skin melanin concentration based on hyperspectral imaging combined with an appropriate analytical model that exploits specific spectral bands to generate maps of melanin content distribution on different Fitzpatrick skin phototypes is presented. Hyperspectral images from the proximal inner side of the forearms of 51 young volunteers covering the first four classes of Fitzpatrick's phototypes were acquired using a hyperspectral imaging system. The images were analyzed using a modified Beer–Lambert law that segregates the contribution of melanin from the other constituents to the skin absorption spectrum. The performance of the model was evaluated using the coefficient of determination (r‐squared). The results revealed that the approach proposed in this study generated accurate melanin concentration distribution maps that allowed a correct classification of skin phototype. In conclusion, the proposed approach for assessing skin melanin concentration proved to be very reliable for classifying skin phototypes, and, as it provides maps that are easily read, it has the advantage of a possible extension of its applications to other research concerning skin pigmentation.

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