“…The rapid clearing of the eruption is also quite unlike the slow resolution of the mucosal lesions of lichen planus. It is of interest that the eruption probably occurred only when the daily dose-of chlorpropamide was raised to 250 mg. Maculopapular eruptions, urticaria, exfoliative dermatitis, erythema multiforme, erythema nodosum, Stevens-Johnson syndrome, photosensitivity, purpura, and proctitis (Rothfeld et al, 1960;Tullett, 1966) have been described as rare skin and epithelial complications of chlorpropamide therapy, but lichenoid eruptions due to this drug do not appear to have been previously reported. Lichenoid eruptions may also occur after treatment with gold, organic arsenic, bismuth, mepacrine, chloroquine, hydrochloroquine, and amiphenazole (Sneddon, 1965;Dinsdale and Walker, 1966), and represent yet another condition in which diagnosis and treatment are greatly helped by knowing what drugs the patient has been taking.…”