Fatal primary cancer of the lung in a teen-age smoker

Sawyer, Kenneth C.; Sawyer, Robert B.; Lubchenco, Alexis E.; McKinnon, Douglas A.; Hill, Kenneth A.

doi:10.1002/1097-0142(1967)20:3<451::aid-cncr2820200313>3.0.co;2-h

Cited by 8 publications

(3 citation statements)

References 4 publications

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“…First, individuals of any age group are at risk from this neoplasm. Indeed, there are occasional reports of this tumour presenting in teenage smokers 5 . Many of the patients in this series had smoked since adolescence, and by their late thirties would already have smoked for 20 years or more.…”

Section: Discussionmentioning

confidence: 78%

Carcinoma of the bronchus in young adults

Seddon

Partridge

1990

Int J Clinical Practice

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SummaryThirty patients with bronchial carcinoma, aged 45 or less, were identified as having attended this or other local chest clinics.In four cases the diagnosis was reached after four or more months of investigations. In two of these cases, pulmonary tuberculosis was incorrectly suspected to be responsible for the illness of the patient.Compared with the disease as it affects all age groups, there appeared to be no greater incidence of any particular presenting symptom. In the group of patients studied, there was an excess of small cell carcinoma compared with that expected.

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Section: Discussionmentioning

confidence: 78%

Carcinoma of the bronchus in young adults

Seddon

Partridge

1990

Int J Clinical Practice

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“…This is particularly true of bronchogenic carcinomas of childhood, like the one described in this case. 3,4 The delay in diagnosis associated with such tumors in children can adversely impact prognosis. 5 Like similar tumors in the adult population, prognosis of primary lung neoplasms in children is commensurate to histology and staging.…”

Section: Discussionmentioning

confidence: 99%

Primary Squamous Cell Carcinoma of the Lung With Bony Metastasis in a 13-year-old Boy

Abuzetun

Hazin

Suker

et al. 2008

Journal of Pediatric Hematology/Oncology

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Primary bronchogenic carcinoma of the lung is extremely rare in children, particularly the squamous cell type. Only 6 cases have been reported in the literature. We are reporting a case of metastatic squamous cell carcinoma in a 13-year-old boy who presented with left shoulder pain secondary to bone metastasis. Given the lack of specific symptoms associated with such malignancies, many children are at risk of delayed diagnosis and, as a result, associated metastases. Diagnostic evaluation hinges on biopsy of suspected lesion and histopathologic evaluation. Treatment regimens are rather ill defined, though the mainstay is surgical resection of the lesion along with chemotherapy and palliative radiotherapy for bone metastasis.

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“…If successful, such a system can be used as a pre-screening tool for all people before some of them need to undergo a thorough clinical checkup. It is a well-known fact that smoking habits degrade lung condition [ 7 , 8 , 9 ] and therefore we tested our tidal-breathing-based approach to see if we can detect or discriminate between smokers’ compromised lungs and non-smokers’ lungs. Thus, our objective resides on evaluating “tidal breathing” only as a marker for lung condition.…”

Section: Introductionmentioning

confidence: 99%

A Novel Approach to the Identification of Compromised Pulmonary Systems in Smokers by Exploiting Tidal Breathing Patterns

Rakshit

Khasnobish

Chowdhury

et al. 2018

Sensors

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Smoking causes unalterable physiological abnormalities in the pulmonary system. This is emerging as a serious threat worldwide. Unlike spirometry, tidal breathing does not require subjects to undergo forceful breathing maneuvers and is progressing as a new direction towards pulmonary health assessment. The aim of the paper is to evaluate whether tidal breathing signatures can indicate deteriorating adult lung condition in an otherwise healthy person. If successful, such a system can be used as a pre-screening tool for all people before some of them need to undergo a thorough clinical checkup. This work presents a novel systematic approach to identify compromised pulmonary systems in smokers from acquired tidal breathing patterns. Tidal breathing patterns are acquired during restful breathing of adult participants. Thereafter, physiological attributes are extracted from the acquired tidal breathing signals. Finally, a unique classification approach of locally weighted learning with ridge regression (LWL-ridge) is implemented, which handles the subjective variations in tidal breathing data without performing feature normalization. The LWL-ridge classifier recognized compromised pulmonary systems in smokers with an average classification accuracy of 86.17% along with a sensitivity of 80% and a specificity of 92%. The implemented approach outperformed other variants of LWL as well as other standard classifiers and generated comparable results when applied on an external cohort. This end-to-end automated system is suitable for pre-screening people routinely for early detection of lung ailments as a preventive measure in an infrastructure-agnostic way.

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Fatal primary cancer of the lung in a teen-age smoker

Cited by 8 publications

References 4 publications

Carcinoma of the bronchus in young adults

Carcinoma of the bronchus in young adults

Primary Squamous Cell Carcinoma of the Lung With Bony Metastasis in a 13-year-old Boy

A Novel Approach to the Identification of Compromised Pulmonary Systems in Smokers by Exploiting Tidal Breathing Patterns

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