Carcinoma of the bronchus in young adults

Seddon, David; Partridge, Martyn R

doi:10.1111/j.1742-1241.1990.tb10722.x

Int J Clinical Practice

1990

DOI: 10.1111/j.1742-1241.1990.tb10722.x

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Carcinoma of the bronchus in young adults

David Seddon

Martyn R Partridge

Abstract: SummaryThirty patients with bronchial carcinoma, aged 45 or less, were identified as having attended this or other local chest clinics.In four cases the diagnosis was reached after four or more months of investigations. In two of these cases, pulmonary tuberculosis was incorrectly suspected to be responsible for the illness of the patient.Compared with the disease as it affects all age groups, there appeared to be no greater incidence of any particular presenting symptom. In the group of patients studied, ther… Show more

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Cited by 3 publications

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Lung Cancer in Patients under 50 Years Old

Tominaga¹,

Mori²,

Yokoi³

et al. 1999

Japanese Journal of Cancer Research

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A long-term retrospective study was carried out on 790 cases of lung cancer to determine if the clinicopathologic characteristics and survival rates of lung cancer patients under the age of 50 differ from those of patients 50 years of age or older at diagnosis by analyzing data on patients registered at Tochigi Cancer Center Hospital. Of the 790 patients, 77 (9.7%) were under the age of 50 at diagnosis. The percentage of women in the younger patient group was significantly higher than that in the older patient group (39.0% vs. 27.5%; P = = = =0.034). Tumor histology revealed a significant preponderance of adenocarcinomas (60 patients, 77.9%) and a paucity of squamous cell carcinomas (8 patients, 10.4%) in the younger age group (P< < < <0.001). The preponderance of adenocarcinoma was significant in both males and females (male: P = = = =0.004, female: P = = = =0.004). Smoking rates and rate of detection by cancer screening did not differ between the two age groups. Because of the paucity of smokers among the younger female patients, causes of lung cancer other than smoking should be sought in younger patients. No difference was found in the stage of the disease at presentation, treatment methods and survival rates between the two age groups. It is suggested that the prognosis for patients with lung cancer under the age of 50 is not significantly worse than for those aged 50 years or older, as has been shown by several investigators.

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Lung Cancer in Patients under 50 Years Old

Tominaga¹,

Mori²,

Yokoi³

et al. 1999

Japanese Journal of Cancer Research

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Effect of Diallyl Disulfide Immobilization on the Immunoreaction of Polysulfone Membranes

Chang

Su²,

Yang

et al. 2009

Textile Research Journal

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Diallyl disulfide (DADS) was covalently bonded to a layer of poly(acrylic acid) grafting on the surface of polysulfone (PSF) membranes. The effects of DADS bonding on oxidative stress, removal of cholesterol, triglyceride and endotoxin, and the ability of thrombus prevention were then evaluated. The surface was characterized with contact angle measurement and Fourier transform infrared spectrometer. Thrombus, platelet aggregation, and oxidative stress were evaluated using human blood. Coagulation times (CT) were evaluated in vitro for hemocompatibility. The production of reactive oxygen species was measured by the chemiluminescence (CL) method to evaluate the oxidative stress. Furthermore, the removal of cholesterol, triglyceride and bacterial endotoxin by DADS-bonding PSF was measured with enzyme-linked immunosorbent assay. The results showed that the DADS-bonding PSF membrane exhibited longer CT, and less adsorption of plasma proteins than the unmodified PSF membrane. In addition, the CL counts of hydrogen peroxide and superoxide values for the DADS-bonding PSF membrane were more stable than those for the unmodified PSF membrane. In addition, the DADS-bonding PSF membrane exhibited ability to remove cholesterol, triglyceride and endotoxin. These results demonstrate that DADS bonding can improve the blood compatibility of PSF membranes. The DADS-bonding PSF membrane could offer protection for patients against oxidative stress and could also reduce the dosage of anticoagulant required during hemodialysis.

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Lung Cancer in Young Adults

Bourke

Milstein

Giura

et al. 1992

Chest

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Carcinoma of the bronchus in young adults

Cited by 3 publications

References 3 publications

Lung Cancer in Patients under 50 Years Old

Lung Cancer in Patients under 50 Years Old

Effect of Diallyl Disulfide Immobilization on the Immunoreaction of Polysulfone Membranes

Lung Cancer in Young Adults

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