Within dynamic and complex construction environments, fatal and non-fatal occupational records are alarming all over the world. Fatigue among workers is one of the key causes which affects their ability to operate safely. To improve safety management, the prevalence of fatigue among workers must be investigated to implement effective interventions for fatigue mitigation. However, the prevalence of fatigue among construction workers in the United States has not been studied. Therefore, this research explores this gap by recruiting 120 workers in the U.S. To achieve the research goals, the worker's level of fatigue (i.e., acute, chronic, and inteshift recovery) was measured using a validated OFER scale. Data analysis revealed (1) the prevalence of fatigue among construction workers is alarming (OFER Score=34.23), that acute fatigue, among all aspects of it, has the most profound impact on workers, and (2) there are no statistical correlations between measured fatigue levels and age and experience of construction workers. The findings of this study will be beneficial to practitioners and researchers in construction to implement effective safety measures to prevent accidents in workplaces.