The static and fatigue characteristics of AS4/PEEK laminates were investigated. Coupons machined from plaques obtained using various molding conditions were tested under monotonic tensile, short beam shear, and three-point flexural fatigue loading. Varying the manufacturing conditions was seen to significantly affect the interlaminar shear strength of the composites, with higher values obtained for the highly crystalline specimens. While for multidirectional laminates the manufacturing conditions seemed to mostly affect the yield stress and the strain and stress to failure, these conditions seem to have only a minor effect on the tensile properties for specimens with unidirectional configurations. The results obtained under fatigue loading, although preliminary, did not show significant dependence on manufacturing parameters.