“…In Brazil, 96% of reported cases of resistance are acquired, as more than half shows a history of three or more previous treatments for tuberculosis. 30,31 The variable, positive HIV test was shown to be a protective factor for tuberculosis in elderly people, probably because this association may be related to the low frequency of HIV positivity in elderly people, who are less vulnerable to the HIV virus. Since TB/HIV co-infection predominates in the economically active age group (from 15 to 50 years old), 32 it may be related to the lifestyle of young adults who adopt behaviors of vulnerability, such as lack of condom use and lack of resulting in increased exposure to HIV and Mycobacterium tuberculosis, resulting in very important economic and social losses, as it reaches the productive stage of the sick individual.…”