At present, the global energy demand keeps rising due to population growth. Therefore, large numbers of photovoltaics (PV) are being integrated with power systems. Solar PV’s installed power capacity is poised to surpass that of coal by 2027, becoming the largest in the world. The integration of PV has changed the direction of the power flow. Under these circumstances, the changed magnitudes and directions of fault current may result in maloperations and non-operations of conventional relays. In this work, a simple and reliable current selective tripping protection scheme is proposed, which is based on the direct communication between overcurrent protective devices on both sides of the line. Through logical programming of the operation information of each protection, the fault location is detected, and the instantaneous trip is realized. The simulation analysis of PSCAD/EMTDC shows that the protection scheme can reliably detect and isolate faults happening at the feeder and bus under different fault conditions; besides, it has good performance in detecting certain resistance grounding faults. The proposed protection scheme can effectively solve the problems caused by PV systems penetration and improve system safety.