Favorable response of reticular erythematous mucinosis to ultraviolet B irradiation using a 308‐nm excimer lamp

Abstract

Reticular erythematous mucinosis (REM) is a rare chronic mucinosis. Histologically, the presence of mucin in the upper dermis is the most specific feature. A 73-year-old woman presented to our outpatient clinic with a 4-year history of netlike macular erythema with slight edema on her left arm. She was diagnosed as having REM on the basis of the clinical picture and histological findings. She was treated with ultraviolet B irradiation using the VTRAC Excimer Lamp system with favorable response. This is the first reported case that was treated with a 308-nm excimer lamp.

Reticular erythematous mucinosis: Literature review and case report of a 24-year-old patient with systemic erythematosus lupus

“…From a total of 96 papers, 37 were eligible for this review summing up 94 previously reported cases. 1,3–37 Adding our case report to the 94 cases (total 95) there were 68 females (71.4%) and 27 males (28.4%). Patients’ ages ranged from 20 to 73 years old (mean = 42).…”

“…Other treatments described were topical and systemic corticosteroids, cyclosporine, calcineurin inhibitors, colchicine, pulsed dye laser, a 308-nm excimer laser, and UVA and UVB phototherapy. 23,27,30,33…”

Reticular erythematous mucinosis: histopathological and immunohistochemical features of 25 patients compared with 25 cases of lupus erythematosus tumidus

“…Usually, the infiltrate of REM is predominantly lymphocytic (helper T cells) admixed with scattered mast cells, histiocytes, neutrophils, eosinophils and plasma cells . In our study, we investigated if there were differences in the lymphocytic subpopulations of REM and LET in an effort to determine whether the lymphocyte subtypes could be diagnostically useful to differentiate the two diseases and suggest different pathogenesis.…”

An unusual clinical presentation of lupus erythematosus tumidus localized on the thigh

“…The differential diagnoses included reticular erythematous mucinosis (REM) and erythema annulare centrifugum (EAC). REM is mainly located on the trunk, although there have been a couple of reports of REM on the arm, and are less frequent reports of arthritis and immunoglobulin deposition . There is a subset of EAC related to lupus erythematosus (LE), which often presents with solitary or few lesions mostly on the trunk and face or proximal extremities.…”