Fear of Progression, Anxiety, and Depression in Patients With Advanced Melanoma in the COVID-19 and Post-COVID-19 Era

Wang, Xiaowen; Li, Min; Shi, Qiong; Ji, Hongchen; Kong, Shengnan; Zhu, Lei; Zhang, Hongmei

doi:10.3389/fpsyt.2022.880978

Cited by 8 publications

(6 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 39 40 The association between depression and FoP remained after adjusting for all other variables in linear regression. This finding was consistent among patients with other types of cancer, including malignant melanoma, 42 cervical cancer, 43 and breast cancer. 44 …”

Section: Discussionsupporting

confidence: 82%

Cancer-Related Dysfunctional Beliefs About Sleep Mediate the Influence of Sleep Disturbance on Fear of Progression Among Patients With Surgically Resected Lung Cancer

Kim

Lee

et al. 2023

J Korean Med Sci

View full text Add to dashboard Cite

Background Lung cancer is associated with significant psychological distress, including fear of progression (FoP). Because insomnia and depression are highly prevalent and associated with FoP, we examined the association between FoP, insomnia, and depression in cancer patients. Furthermore, we tested the mediation effect of cancer-related dysfunctional beliefs about sleep (C-DBS) on this association. Methods We analyzed data collected from patients with surgically resected non-small cell lung cancer from a single-center randomized controlled study investigating digital healthcare applications. Baseline demographic and clinical variables were collected. In addition, self-reported questionnaires including the Fear of Progression Questionnaire-Short Form, Patients Health Questionnaire-9 items (PHQ-9), Insomnia Severity Index, and C-DBS were administered. Results Among the 320 enrolled patients with lung cancer, a regression model showed that FoP was predicted by age (β = −0.13, P = 0.007), PHQ-9 (β = 0.35, P < 0.001), and C-DBS (β = 0.28, P < 0.001). Insomnia did not directly influence FoP, but C-DBS mediated the association. Depression directly influenced FoP, but C-DBS did not mediate this association. Conclusion Among patients with surgically resected lung cancer, C-DBS mediated the effects of severity of insomnia on FoP. Depression directly influenced FoP, but C-DBS did not influence this association. To reduce FoP among patients with lung cancer, C-DBS should be addressed in the cognitive behavioral therapy module.

show abstract

Section: Discussionsupporting

confidence: 82%

Cancer-Related Dysfunctional Beliefs About Sleep Mediate the Influence of Sleep Disturbance on Fear of Progression Among Patients With Surgically Resected Lung Cancer

Kim

Lee

et al. 2023

J Korean Med Sci

View full text Add to dashboard Cite

show abstract

“…Of the 303 participants, 88 (29.04%) were found to meet the diagnostic criteria for dysfunctional FoP, suggesting that the psychological impact of FoP among PLWHIV should be given greater attention. The FoP-Q-SF has been widely used to assess FoP in patients, particularly those with cancer and other chronic diseases [ 8 , 27 – 29 ]. The prevalence of dysfunctional FoP among cancer patients has been found to range from 5.1% in patients with multiple types of cancer to 68.4% in breast cancer patients [ 9 , 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…FoP is a significant mental health issue that has been studied first among diseases such as cancer, diabetes mellitus and rheumatic diseases [ 7 ]. Previous research has shown that FoP levels differ depending on the tumor stage among cancer patients [ 8 , 9 ]. However, to date, no studies have investigated the level of FoP among PLWHIV at different stages of HIV infection.…”

Section: Introductionmentioning

confidence: 99%

The association between fear of progression and medical coping strategies among people living with HIV: a cross-sectional study

Li,

Lin,

Chen

et al. 2024

BMC Public Health

View full text Add to dashboard Cite

Background Due to the chronic nature of HIV, mental health has become a critical concern in people living with HIV (PLWHIV). However, little knowledge exists about the association between fear of progression (FoP) and medical coping modes (MCMs) in PLWHIV in China. Methods A cohort of 303 PLWHIV were consecutively enrolled and their demographic, clinical and psychological information was collected. The Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Social Support Rating Scale (SSRS), Internalized HIV Stigma Scale (IHSS) and MCMs Questionnaire were utilized. Results Of the participants, 215 PLWHIV were classified into the low-level FoP group, and 88 were grouped into the high-level FoP group based on their FoP-Q-SF scores, according to the criteria for the classification of dysfunctional FoP in cancer patients. The high-level group had a higher proportion of acquired immunodeficiency syndrome (AIDS) stage (P = 0.005), lower education levels (P = 0.027) and lower income levels (P = 0.031). Additionally, the high-level group had lower scores in social support (P < 0.001) and its three dimensions, with total SSRS scores showing a negative correlation with two dimensions of FoP-Q-SF, namely physical health (r2 = 0.0409, P < 0.001) and social family (r2 = 0.0422, P < 0.001). Further, the high-level group had higher scores in four dimensions of internalized HIV stigma, and a positive relationship was found to exist between IHSS scores and FoP-Q-SF scores for physical health (r2 = 0.0960, P < 0.001) and social family (r2 = 0.0719, P < 0.001). Social support (OR = 0.929, P = 0.001), being at the AIDS stage (OR = 3.795, P = 0.001), and internalized HIV stigma (OR = 1.028, P < 0.001) were independent factors for FoP. Furthermore, intended MCMs were evaluated. FoP were positively correlated with avoidance scores (r2 = 0.0886, P < 0.001) and was validated as the only factor for the mode of confrontation (OR = 0.944, P = 0.001) and avoidance (OR = 1.059, P = 0.001) in multivariate analysis. Conclusion The incidence of dysfunctional FoP in our study population was relatively high. High-level FoP was associated with poor social support, high-level internalized HIV stigma and a negative MCM among PLWHIV.

show abstract

“…This study found that quality of life and psychological state were impaired during COVID-19 lockdowns, with a significantly higher number of confirmed anxiety cases in patients for whom treatment was delayed or cancelled [ 33 ]. In patients with melanoma specifically, a recent cross-sectional study assessed psychological outcomes during the COVID-19 pandemic in China and found that patients with melanoma experienced heightened fear of progression, increased depression, and elevated anxiety during the pandemic [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

Prioritizing Melanoma Surgeries to Prevent Wait Time Delays and Upstaging of Melanoma during the COVID-19 Pandemic

Aw,

Lau,

Nessim

2023

Current Oncology

View full text Add to dashboard Cite

Prompt diagnosis and surgical management of melanoma strongly impact prognosis. Considering the limited resources, emergency closures, and staffing shortages during the COVID-19 pandemic in Canada, our institution implemented a dedicated care pathway to prioritize cancer surgeries. We aim to assess whether this strategy was effective at preventing surgical wait time delays and upstaging of melanoma. We retrospectively collected data of patients aged ≥18 years with biopsy-proven primary melanoma who underwent wide local excision (WLE) ± sentinel lymph node biopsy (SLNB) between 1 March 2018–29 February 2020 (pre-pandemic) and 1 March 2020–22 March 2022 (pandemic). Patients with distant metastasis, recurrence, in situ disease, and unknown primary were excluded. Wait time from consult to surgery, tumour (T) and nodal (N) stage, and overall stage were collected. Results: We included 419 patients [pre-pandemic (n = 204) and pandemic (n = 215)]. Median wait time (days) [interquartile range] to surgery was 36 [22–48] pre-pandemic and 35 [24–49] during the pandemic (p = 0.888). There were no differences found in T stage (p = 0.060), N stage (p = 0.214), or overall melanoma stage (p = 0.192). We highlight the importance of streamlining melanoma surgery during a pandemic. As the need arises to meet surgical backlogs including benign surgery, dedicated cancer surgery should maintain a priority to not negatively affect cancer outcomes.

show abstract

Fear of Progression, Anxiety, and Depression in Patients With Advanced Melanoma in the COVID-19 and Post-COVID-19 Era

Cited by 8 publications

References 57 publications

Cancer-Related Dysfunctional Beliefs About Sleep Mediate the Influence of Sleep Disturbance on Fear of Progression Among Patients With Surgically Resected Lung Cancer

Cancer-Related Dysfunctional Beliefs About Sleep Mediate the Influence of Sleep Disturbance on Fear of Progression Among Patients With Surgically Resected Lung Cancer

The association between fear of progression and medical coping strategies among people living with HIV: a cross-sectional study

Prioritizing Melanoma Surgeries to Prevent Wait Time Delays and Upstaging of Melanoma during the COVID-19 Pandemic

Contact Info

Product

Resources

About