2021
DOI: 10.1136/bmjopen-2020-042823
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Feasibility and acceptability of a multi-domain intervention to increase Mediterranean diet adherence and physical activity in older UK adults at risk of dementia: protocol for the MedEx-UK randomised controlled trial

Abstract: IntroductionDementia prevalence continues to increase, and effective interventions are needed to prevent, delay or slow its progression. Higher adherence to the Mediterranean diet (MedDiet) and increased physical activity (PA) have been proposed as strategies to facilitate healthy brain ageing and reduce dementia risk. However, to date, there have been no dementia prevention trials in the UK focussed on combined dietary and PA interventions. This study aims to: (1) assess feasibility and acceptability of a the… Show more

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Cited by 17 publications
(16 citation statements)
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“…Similarly, MedEx, is a recently completed RCT which has examined the feasibility of adopting a MDP and a MDP plus PA intervention in UK adults at risk of agerelated cognitive decline. MedEx utilised strategies including self-selected dietary targets, group sessions, digital support and food deliveries to help individuals make and sustain healthy lifestyle choices (34) . The lack of research evidence and potential benefits of a combined MDP and PA was reviewed by Hershey and colleagues (35) .…”
Section: Mdp Adoption Approachesmentioning
confidence: 99%
“…Similarly, MedEx, is a recently completed RCT which has examined the feasibility of adopting a MDP and a MDP plus PA intervention in UK adults at risk of agerelated cognitive decline. MedEx utilised strategies including self-selected dietary targets, group sessions, digital support and food deliveries to help individuals make and sustain healthy lifestyle choices (34) . The lack of research evidence and potential benefits of a combined MDP and PA was reviewed by Hershey and colleagues (35) .…”
Section: Mdp Adoption Approachesmentioning
confidence: 99%
“…The workshop was delivered as two half‐day virtual events, held on the 28th September 2020 and the 17th February 2021. Prior to the first meeting, the following documents were provided to all registered participants to show the relevant policy and scientific background to the NuLifE remit. A summary of the workshop bid to the MRC Infographic of the UK Eatwell Guide (PHE, 2016a) Public Health England's dietary recommendations for the UK 2016 (PHE, 2016b) Mortality and life expectancy trends in the UK (Marshall et al, 2019) Advancing our Health: Prevention in the 2020s (Department of Health & Social Care, 2019) World Health Organization: Risk reduction of cognitive decline and dementia 2019 (WHO, 2019) Schulze M et al, Food based dietary patterns and chronic disease prevention (Schulze et al, 2018) Scheelbeek P, Dangour A et al, Health impacts and environmental footprints of diets that meet the Eatwell Guide recommendations: analyses of multiple UK studies (Scheelbeek et al, 2020) Slide sets summarising previous nutrition randomised controlled trials ( Nu ‐ AGE , CRESSIDA , PREDIMED , Food4Me , MedEx ) (Berendsen et al, 2018; Celis‐Morales et al, 2017; Estruch et al, 2018; Reidlinger et al, 2015; Shannon et al, 2021) …”
Section: Workhops Structurementioning
confidence: 99%
“…Prior to the first meeting, the following documents were provided to all registered participants to show the relevant policy and scientific background to the NuLifE remit. (Berendsen et al, 2018;Celis-Morales et al, 2017;Estruch et al, 2018;Reidlinger et al, 2015;Shannon et al, 2021) NULIFE WORKSHOP 1…”
Section: Workhops Structurementioning
confidence: 99%
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“…A secondary cross-sectional analysis of baseline data from 91 adults aged 54–74y at recruitment in the MedEx-UK study (6) was performed. MedDiet adherence was defined by the 14-item Mediterranean Diet Adherence Screener (MEDAS) questionnaire, and participants were dichotomised into higher and lower adherence groups at the sample-specific median MEDAS score.…”
mentioning
confidence: 99%