Feasibility of a home-based exercise intervention with remote guidance for patients with stable grade II and III gliomas: a pilot randomized controlled trial

Gehring, Karin; Kloek, Corelien; Aaronson, Neil K.; Janssen, Kasper W; Jones, Lee W.; Sitskoorn, Margriet M.; Stuiver, Martijn M.

doi:10.1177/0269215517728326

Cited by 76 publications

(128 citation statements)

References 37 publications

Supporting

Mentioning

124

Contrasting

Unclassified

Order By: Relevance

“…At follow-up, our case improved aerobe power (24%), muscle strength (0-38%), walking ability (9%), and standing balance (71%). This indicates that exercise rehabilitation can improve functional performance as previously reported [24,40,41,43,44]. He also improved 'Global Health Status/QOL' by 8.4 points and 'Physical functioning' by 6.7 points.…”

Section: Exercise Interventionsupporting

confidence: 80%

“…However, performance status and age are among the best described prognostic factors in GBM, and most likely there is a strong relation between highperformance status and lower age [37]. Mean age in studies of patients with gliomas attending outpatient rehabilitation or physical capacity assessments ranges between 34 and 61 [7,26,28,38,39,40,41,42,43,44]. This implies that exercise rehabilitation intervention mainly addresses the younger population or patients with high Karnofsky performance status, which makes our case highly representative of this glioma population.…”

Section: Exercise Interventionmentioning

confidence: 99%

See 1 more Smart Citation

Development of an exercise intervention as part of rehabilitation in a glioblastoma multiforme survivor during irradiation treatment: a case report

Hansen

Søgaard

Minet

2018

Disability and Rehabilitation

View full text Add to dashboard Cite

Based on this single case, exercise rehabilitation has the ability to maintain or improve functional performance and QOL domains even during heavy treatments. It also implies that patients with GBM are capable and may be willing to participate in exercise rehabilitation if supervised by physical therapists. Implications for rehabilitation The use of exercise as part of rehabilitation still needs attention in strong methodology studies of patients with gliomas. Exercise rehabilitation may maintain or even improve functional performance and QOL domains during medical treatment regimens. Functional independent patients with GBM are capable to comply with generic exercise recommendations and may be willing to participate in exercise rehabilitation if supervised by physical therapists.

show abstract

Section: Exercise Interventionsupporting

confidence: 80%

Section: Exercise Interventionmentioning

confidence: 99%

Development of an exercise intervention as part of rehabilitation in a glioblastoma multiforme survivor during irradiation treatment: a case report

Hansen

Søgaard

Minet

2018

Disability and Rehabilitation

View full text Add to dashboard Cite

show abstract

“…However, 3 exercise sessions weekly for 6 months were feasible in glioma patients undergoing treatment and increased overall fitness. 32 Exercise was also found to be feasible in a sample of patients with advanced cancers, some of which were glioblastoma; exercise improved quality of life at end-of-life as well. 33 Lack of randomized controlled trials in the brain tumor population does not preclude prescribing exercise as an intervention to prevent fatigue and other tumor-and treatment-related problems.…”

Section: Prescriptive Interventionsmentioning

confidence: 98%

“…37 A downloadable application for cognitive rehabilitation is currently under study that may be of interest to those who regularly use smart technology. 56,57 Additional enhancements to cognitive rehabilitation programs include use of virtual reality. Yang used a virtual reality experience as part of a cognitive rehabilitation program in 38 patients.…”

Section: Prescriptive Interventionsmentioning

confidence: 99%

Symptom-based interventions to promote quality survivorship

Amidei

2018

Neuro-Oncology

View full text Add to dashboard Cite

Survival alone is no longer an adequate outcome for persons with brain tumors; the quality of the survivorship experience should be viewed with equal importance. Symptom management is a significant component of quality survivorship care. Regardless of their histology, brain tumors and therapies used to treat them produce symptoms that affect an individual's ability to function in everyday life. Common symptoms include fatigue, cognitive impairment, distress, and sleep disturbance. Symptom-based interventions for persons with brain tumors focus on prevention, self-management, and prescriptive interventions targeted to these problems. Unfortunately, little evidence exists to support many interventions, making it challenging for clinicians to provide concrete recommendations. Research is needed to provide evidence in support of symptom-based interventions while novel approaches to these challenging problems are developed.

show abstract

“…Head and neck cancer patients were recruited from the Department of Hematology and Oncology at the National Cheng Kung University Hospital, Tainan, Taiwan. The patient sample size was referred by previous cancer exercise reports (17,18). The characteristics of the studied population are presented in Table 1.…”

Section: Subjectsmentioning

confidence: 99%

Effect of Exercise Training on Exercise Tolerance and Level of Oxidative Stress for Head and Neck Cancer Patients Following Chemotherapy

et al. 2020

View full text Add to dashboard Cite

Background: Chemotherapy decreases fitness performance via repression of cardiopulmonary function and oxidative stress. This study was designed to investigate whether exercise intervention could improve exercises capacity and reduce systemic oxidative stress in patients with head and neck (H&N) cancer receiving chemotherapy. Methods: This is a single-center study. Forty-two H&N cancer patients who were undergoing chemotherapy were recruited in this study. An 8-week exercise intervention was performed by conducting the combination of aerobic and resistance exercise 3 days a week. The exercise training was conducted by a physiotherapist. The exercise capacity and exercise responses were measured from blood pressure (BP) and heart rate (HR). Oxidative stress markers from human plasma, such as total antioxidant capacity, 8-hydroxy-2-deoxyguanosine, malondialdehyde, and carbonyl content, were tested by activity kits. Results: We provide compelling evidence that exercise training ameliorated exercise responses and increased exercise capacity by repressing resting BP and increasing 1and 3-min BP recovery. We also found the resting HR was reduced, and the 1-and 3min HR recovery was increased after exercise training. In addition, the rating of perceived exertion after the peak exercise was reduced after exercise intervention. We also found that exercise training repressed oxidative stress markers by elevation of total antioxidant capacity and suppression of 8-OHd and carbonyl content in plasma. Discussion: We clearly demonstrate that exercise can promote exercise capacity and reduce oxidative stress in H&N cancer patients receiving chemotherapy, which might guide new therapeutic approaches for cancer patients, especially those undergoing chemotherapy.

show abstract

Feasibility of a home-based exercise intervention with remote guidance for patients with stable grade II and III gliomas: a pilot randomized controlled trial

Cited by 76 publications

References 37 publications

Development of an exercise intervention as part of rehabilitation in a glioblastoma multiforme survivor during irradiation treatment: a case report

Development of an exercise intervention as part of rehabilitation in a glioblastoma multiforme survivor during irradiation treatment: a case report

Symptom-based interventions to promote quality survivorship

Effect of Exercise Training on Exercise Tolerance and Level of Oxidative Stress for Head and Neck Cancer Patients Following Chemotherapy

Contact Info

Product

Resources

About