Feasibility of knitted carbon/PEEK composites for orthopedic bone plates

Fujihara, K.; Huang, Zheng‐Ming; Ramakrishna, S.; Satknanantham, K.; Hamada, Hiroyuki

doi:10.1016/j.biomaterials.2003.10.050

Cited by 84 publications

(50 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Novel ceramic structures, such as self-assembled ceramic multilayers (Karlinsey et al 2006) or biomorphic ceramic constructed on polysaccharide templates from cellulose (Muller et al 2006), are being developed that should be useful in biotechnology and tissue engineering. As alternatives to metal implants, novel organic polymer materials have been developed, for example, from polyetheretherketone, which mimics anisotropic features of bone (Fujihara et al 2004). …”

Section: Porous Scaffoldsmentioning

confidence: 99%

Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix

et al. 2009

View full text Add to dashboard Cite

The ultimate goal in the design of biomimetic materials for use in tissue engineering as permanent or resorbable tissue implants is to generate biocompatible scaffolds with appropriate biomechanical and chemical properties to allow the adhesion, ingrowth, and survival of cells. Recent efforts have therefore focused on the construction and modification of biomimetic surfaces targeted to support tissue-specific cell functions including adhesion, growth, differentiation, motility, and the expression of tissue-specific genes. Four decades of extensive research on the structure and biological influence of the extracellular matrix (ECM) on cell behavior and cell fate have shown that three types of information from the ECM are relevant for the design of biomimetic surfaces: (1) physical properties (elasticity, stiffness, resilience of the cellular environment), (2) specific chemical signals from peptide epitopes contained in a wide variety of extracellular matrix molecules, and (3) the nanoscale topography of microenvironmental adhesive sites. Initial physical and chemical approaches aimed at improving the adhesiveness of biomaterial surfaces by sandblasting, particle coating, or etching have been supplemented by attempts to increase the bioactivity of biomaterials by coating them with ECM macromolecules, such as fibronectin, elastin, laminin, and collagens, or their integrin-binding epitopes including RGD, YIGSR, and GFOGER. Recently, the development of new nanotechnologies such as photo- or electron-beam nanolithography, polymer demixing, nano-imprinting, compression molding, or the generation of TiO(2) nanotubes of defined diameters (15-200 nm), has opened up the possibility of constructing biomimetic surfaces with a defined nanopattern, eliciting tissue-specific cellular responses by stimulating integrin clustering. This development has provided new input into the design of novel biomaterials. The new technologies allowing the construction of a geometrically defined microenvironment for cells at the nanoscale should facilitate the investigation of nanotopography-dependent mechanisms of integrin-mediated cell signaling.

show abstract

Section: Porous Scaffoldsmentioning

confidence: 99%

Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Additional biomechanical studies to verify which design can be best fitted for orthopedic purposes had been performed on different fiber orientations of CF-PEEK bone plates (Fujihara et al, 2003(Fujihara et al, , 2004. Although there are some clinical and animal studies that used carbon fiber plates for trauma, no intramedullary nails or plates were clinically tested or used with the CF-PEEK Optima composite thus far (Baker et al, 2004;Pemberton et al, 1992;Rohner et al, 2005;Tayton et al, 1982).…”

Section: Introductionmentioning

confidence: 98%

Carbon fiber reinforced PEEK Optima—A composite material biomechanical properties and wear/debris characteristics of CF-PEEK composites for orthopedic trauma implants

Steinberg

Rath

Shlaifer

et al. 2013

Journal of the Mechanical Behavior of Biomedical Materials

196

112

View full text Add to dashboard Cite

“…They have determined that the longitudinal strain in bone and the bone plate are higher with composite plate than that with steel plate for a given loading. Fujihara et al (2004) have reported that knitted carbon/PEEK fabric composites are considered as a candidate for bone-plate application. Ganesh et al (2005) have proposed to use stiffnessgraded plates in order to solve the problems caused by compressive stress-shielding at the fracture-interface immediately after fracture-fixation.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of bone plate with low-stiffness material in terms of stress distribution

Benli

Aksoy

Havıtçıoğlu

et al. 2008

Journal of Biomechanics

116

View full text Add to dashboard Cite

Feasibility of knitted carbon/PEEK composites for orthopedic bone plates

Cited by 84 publications

References 38 publications

Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix

Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix

Carbon fiber reinforced PEEK Optima—A composite material biomechanical properties and wear/debris characteristics of CF-PEEK composites for orthopedic trauma implants

Evaluation of bone plate with low-stiffness material in terms of stress distribution

Contact Info

Product

Resources

About