Feasibility of the Allergy Questionnaire for Athletes (AQUA<sup>©</sup>) in pediatric age

Fasola, Salvatore; Bellafiore, Marianna; Baiardini, Ilaria; Bonini, Matteo; Giacco, Stefano Del; Ferrante, Giuliana; Grutta, Stefania La

doi:10.1111/pai.13006

Cited by 4 publications

(3 citation statements)

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“…Differently from the previous validation study in children aged 12‐14 years, 2 where the items and the scoring system were borrowed from the adult version, 9 in the current study, a new scoring system was derived starting from an age‐specific version of the questionnaire 12 . AQUAped ≥ 2 had 82% specificity and 60% sensitivity, while only 5% of non‐atopic children had AQUAped ≥ 24.…”

Section: Discussionmentioning

confidence: 99%

“…AQUAped 12 is a shortened and linguistically simplified version of AQUA © 9 composed of 25 items; the 12 questions with a potential value in predicting atopy (5‐14 and 16‐17) will be referred to as the core items . AQUAped is provided as a .…”

Section: Methodsmentioning

confidence: 99%

“…2 In this regard, it is known that children would require age-specific instruments, adapted to their still-developing cognitive and linguistic skills. 11 Recently, good feasibility of a paediatric version of AQUA © (AQUAped) was demonstrated in a large sample of children (7-10 years) and adolescents (11-14 years) athletes, 12 but its validity and repeatability were not tested yet. The objectives of this study were as follows: (i) to develop a scoring system for AQUAped; (ii) to identify the optimal age target within the range 7-14 years; (iii) to assess AQUAped validity for the screening of atopy and its repeatability in the identified target population.…”

Section: Introductionmentioning

confidence: 99%

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Validity and repeatability of the Pediatric Allergy Questionnaire for Athletes (AQUAped) for the screening of atopy

Fasola

Ferrante

Malizia

et al. 2020

Pediatric Allergy Immunology

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Background: High atopy prevalence has been reported in athletes. Having an agespecific questionnaire for predicting atopy is important for an optimal management of young athletes. The study objectives were as follows: (i) developing a scoring system for the Pediatric Allergy Questionnaire for Athletes (AQUAped); (ii) identifying the optimal age target within the range 7-14 years; (iii) assessing AQUAped validity and repeatability in the identified target population. Methods: A total of 133 young athletes (age 7-14 years) were recruited. Following a screening visit, the participants filled AQUAped at baseline (T0) and after 7 days (T1), concomitantly undergoing skin prick testing. Using atopy as the gold standard (positivity to ≥1 aeroallergen), the 12 core items were scored based on their likelihood ratios, and a total score was calculated. The optimal cutoff was identified based on the Youden's criterion. The repeatability of AQUAped was assessed through the intra-cluster correlation coefficient (ICC). The optimal age target was identified as the largest age range associated with an acceptable cross-validated area under the receiver operating characteristic curve (AUC ≥ 0.70) and an excellent ICC (≥0.75). Results: Forty (30%) children were atopic; the optimal age target was 10-14 years (cross-validated AUC = 0.70, ICC = 0.81). AQUAped total score ranged from −26 to 75, and only 5% of non-atopic children had AQUAped ≥ 24. AQUAped ≥ 2 had 82% specificity, 60% sensitivity, and 74% overall accuracy. Conclusion: Developing and testing a scoring system for AQUAped showed that it is a valid and reliable tool for the screening of atopy in young athletes aged 10-14 years.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%