“…We anticipate that such situations are quite common, and impede the discovery of many new embedded patterns in regional cortical folds at various brain regions. In our future work, we hope to test this issue further, and computationally extend this framework by including feature subset selection procedures (Bolón-Canedo & Remeseiro, 2020; Chandrashekar & Sahin, 2014; Hua et al, 2005; Miao & Niu, 2016; Roy, Schaffer, & Laramee, 2015; Way, Sahiner, Hadjiiski, & Chan, 2010; Xue, Zhang, Browne, & Yao, 2016), so that investigators will have added guidance in order to narrow down on the set of physical attributes of a cortical fold that best explain the set of embedded shapes.…”