Features of cerebral stroke course in patients with diabetes mellitus according to the REGION-M register

Воронина, В. П.; Загребельный, А. В.; Лукина, Ю. В.; Кутишенко, Н. П.; Дмитриева, Н. А.; Лерман, О. В.; Лукьянов, М. М.; Окшина, Е. Ю.; Благодатский, С. В.; Иванова, Л. П.; Бойцов, С. А.; Драпкина, О. М.; Марцевич, С. Ю.

doi:10.15829/1728-8800-2019-5-60-65

Cited by 9 publications

(6 citation statements)

References 9 publications

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“…Расходы на медицинскую помощь и риск госпитализации больных, которую можно было бы предотвратить, резко возрастают с увеличением числа сочетанных заболеваний (коморбидности) [1]. В регистре РЕГИОН-М (РЕГИстр больных, перенесших Острое Нарушение мозгового кровообращения и госпитализированных в московский стационар) госпитальная летальность после ОНМК у пациентов с сахарным диабетом (СД) была достоверно выше [8]. Учитывая высокую социальную значимость инсульта и ИБС, изучение прогноза жизни пациентов с сочетанием данных патологий в рамках амбулаторно-поликлинической части регистра РЕГИОН-М представляется актуальной задачей.…”

Section: результатыunclassified

“…Подробно протокол госпитально-поликлинического регистра РЕГИОН был опубликован ранее [8,9]. Были использованы данные амбулаторной проспективной части регистра РЕГИОН-М, в которую включены 684 пациента, прикрепленных к Городской поликлинике № 64 г. Москвы, выписанных из "Городской клинической больницы им.…”

Section: материал и методыunclassified

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Long-term survival of patients after cerebrovascular accident with prior coronary artery disease: data from the outpatient stage of REGION-M registry

Толпыгина¹,

Чернышева

Воронина³

et al. 2022

Cardiovasc Ther Prev

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Aim. To study two-year survival and factors affecting it in patients with cerebrovascular accident (CVA) with prior coronary artery disease (CAD).Material and methods. The outpatient stage of the REGION-M registry included 684 patients assigned to the Moscow City Polyclinic № 64, discharged from the F.I. Inozemtsev City Clinical Hospital in the period from January 1, 2012 to April 30, 2017 with a verified diagnosis of stroke or transient ischemic attack. Of these, 423 (61,8%) patients had a diagnosis of CAD in the outpatient records.Results. Patients with CAD were significantly older, more often had comorbidities, disability, and were monitored in the polyclinic before the stroke and after hospital discharge than patients without CAD. During the follow-up period, mortality among patients with CAD (34,3%) was significantly higher than without CAD (19,9%) (p< 0,01), At the same time, mortality in CAD was 2,6 times lower among patients who applied to the polyclinic at least once after discharge (28%) than those who never applied after discharge — 72,9% (p< 0,001), Multivariate analysis confirmed this positive effect (relative risk, 0,998; confidence interval: 0,983-0,992, p< 0,0001).Conclusion. Mortality in patients with stroke and CAD was significantly higher than in those without CAD, while it was significantly lower among patients monitored in the polyclinic in the post-hospital period of stroke.

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Section: результатыunclassified

Section: материал и методыunclassified

Long-term survival of patients after cerebrovascular accident with prior coronary artery disease: data from the outpatient stage of REGION-M registry

Толпыгина¹,

Чернышева

Воронина³

et al. 2022

Cardiovasc Ther Prev

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“…Подробно протокол всего госпитально-поликлинического ретроспективно-проспективного регистра РЕГИОН и отдельных его частей был опубликован ранее [11][12][13] Adherence to Attendance at Outpatient Clinic Приверженность посещению поликлиники За 2 года наблюдения по данным ЕМИАС умерло 28,8% (197 из 684) пациентов, выписанных из стационара после перенесенного ОНМК. Среди умерших доля мужчин была меньше, чем женщин (37,6% против 62,4%, p<0,001).…”

Section: материал и методыunclassified

Adherence to Attendance at Outpatient Clinic and Longterm Survival of Patients after Stroke in Outpatient Setting: the Data of REGION-M Registry

Martsevich¹,

Толпыгина²,

Чернышева

et al. 2021

Racionalʹnaâ farmakoterapiâ v kardiologii

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Aim. Assess the two-year survival rate of patients who have undergone acute cerebral circulation disorder, depending on their commitment to visiting the district polyclinic before and after discharge from the hospital.Material and methods. The outpatient part of the REGION-M register included 684 patients attached to the Moscow City Polyclinic №64, discharged from the Moscow City Clinical Hospital n.a. F.I. Inozemtsev of from 01.01.2012 to 04.30.2017 with a confirmed diagnosis of acute cerebral circulation disorder (cerebral stroke / transient ischemic attack).Results. Of the entire cohort, 83.2% of patients and 84.2% after hospital discharge attended the clinic during the year before the development of reference acute cerebral circulation disorder. Patients who attended the clinic before and after the reference stroke were older, more likely to have diabetes, comorbid disease and disability. For 22 months of follow-up, mortality was 28.8% (197 out of 684 people). Among those who applied and did not apply to the clinic before the reference acute cerebral circulation disorder, the difference in mortality tended to be reliable (27.4% versus 35.7%, p <0.1), while mortality was almost twice as low among patients who applied to the clinic at least 1 time after discharge (25.7%) than among patients who did not apply after discharge - 45.4%, p<0.0001. When adjusting for sex and age (the relative risk of death for them was 1.009, 95% confidence interval 1.005-1.01 2, p<0.0001 ), the statistical validity of reducing the risk of death was maintained when patients were committed to visiting the clinic after discharge - the relative risk of death 0.366 (95% confidence interval 0.269-0.500, p<0.0001 ).Conclusion. Lower mortality among those who visited the district polyclinic after undergoing stroke confirms the important role of medical observation in the posthospital period. At the same time, there is a reserve in improving the long-term prognosis of the lives of patients who have suffered a cerebral stroke or transient ischemic attack, due to greater coverage of patients with medical supervision in the clinic.

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“…Подробно протокол всего госпитально-поликлинического регистра РЕГИОН и отдельных его частей был опубликован ранее [10][11][12]. В настоящем фрагменте исследования использованы данные амбулаторной части регистра РЕГИОН-М, в которую были включены все пациенты, прикрепленные к Городской поликлинике № 64 ДЗМ г. Москвы, выписанные из "ГКБ им.…”

Section: материал и методыunclassified

Quality of medication therapy in patients after stroke depending on presence/absence of diabetes: data from the outpatient stage of REGION-M registry

Марцевич¹,

Толпыгина²,

Загребельный³

et al. 2021

Cardiovasc Ther Prev

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Aim. To assess the quality of medication treatment in the polyclinic within 2 years after discharge, depending on presence/absence of diarecommended for patients with stroke before its development and betes.Material and methods. The study included 684 patients assigned to the City Polyclinic № 64 (Moscow), discharged from F.I. Inozemtsev City Clinical Hospital (Moscow) for a period from January 1, 2012 to April 30, 2017 with a diagnosis of stroke/transient ischemic attack, of which 122 were diagnosed with diabetes.Results. Before stroke, therapy was recommended for 67,3% of patients with diabetes and 54,7% without diabetes (p<0,01): statins — 15,5 and 14,4%, antiplatelet agents — 32,7 and 25,5%, angiotensinconverting enzyme (ACE) inhibitors/angiotensin II receptor blockers (ARBs) — 41,4 and 37,9%, beta-blockers (BBs) — 9,1% and 7,8%, respectively. For the first 6 months after stroke, the rate of statin therapy increased to 39,6 and 39,2%, antiplatelet drugs — to 62,6 and 51,9%, ACE inhibitors/ARBs — to 68,2 and 66%, BBs — to 51,6 and 37,2%, respectively. Then, after 6 months it decreased again to 28,8 and 27,1% for statins, to 30,7 and 35,2% for antiplatelet agents, to 43,3 and 42,6% for ACE inhibitors/ARBs and remained the same for BBs, respectively. There were no significant differences in the prevalence of prescribing most drugs to patients with and without diabetes, both before and after stroke, with the exception of hypoglycemic medications.Conclusion. The therapy of patients with previous stroke, both with and without diabetes, recommended in the polyclinic, is characterized by an insufficient prescription rate of main drug classes necessary for secondary cardiovascular prevention at all follow-up stages.

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Features of cerebral stroke course in patients with diabetes mellitus according to the REGION-M register

Cited by 9 publications

References 9 publications

Long-term survival of patients after cerebrovascular accident with prior coronary artery disease: data from the outpatient stage of REGION-M registry

Long-term survival of patients after cerebrovascular accident with prior coronary artery disease: data from the outpatient stage of REGION-M registry

Adherence to Attendance at Outpatient Clinic and Longterm Survival of Patients after Stroke in Outpatient Setting: the Data of REGION-M Registry

Quality of medication therapy in patients after stroke depending on presence/absence of diabetes: data from the outpatient stage of REGION-M registry

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