Features of clinical picture of pneumonia caused by SARS-COV-2 virus in children

BACKGROUND:During the coronavirus pandemic, one of the most important areas of scientific research was the study of laboratory parameters, as well as calculated indices that could be used as criteria reflecting the course of the infectious process, and could be used as predictors of severe course and adverse outcome of the disease. AIM:Assessment of hematological parameters in children with COVID-19 in the Republic of Sakha (Yakutia). MATERIALS AND METHODS:The article presents data from a retrospective study of 344 cases of a new coronavirus infection caused by the COVID-19 virus (ICD-10 code U07.1) in children hospitalized in the period from 03/23/202012/27/2020 in the Childrens Infectious Clinical Hospital of Yakutsk. RESULTS:The results of the study showed that upon admission to the hospital, the proportion of children with reduced leukocyte levels exceeded the proportion of children with leukocytosis (23 versus 10%), there were reduced hemoglobin levels, changes in the content of platelets, segmented neutrophils, lymphocytes. The rate of erythrocyte sedimentation was increased in 48% of children. Neutrophilia and lymphopenia were associated with the severity of the childrens condition. The values of the ratio of neutrophils to lymphocytes in some age groups were associated with the severity of the condition of children. CONCLUSIONS:The infectious process in children with a new coronavirus infection is accompanied by a change in the leukocyte formula, an increase in ESR and a change in the platelet content. Neutrophilia and lymphopenia are associated with the severity of the condition of children.

show abstract

Assessment of hematological parameters in children with COVID-19 in the Republic of Sakha (Yakutia)

Evseeva

Климова

Bogdashin

et al. 2023

Pediatr (SPb)

View full text Add to dashboard Cite

show abstract

Features of the course of COVID-19 in children with the spread of the Omicron variant

Ruzhentsova,

Garbuzov,

Bitsueva

et al. 2024

APPS

View full text Add to dashboard Cite

The aim of the study was to assess the symptoms and identify risk factors for prolonged and complicated COVID-19 during the spread of the Omicron variant in children aged 1 month to 18 years. Materials and methods. The study included 110 children with confirmed COVID-19 of mild or moderate severity at the time of the first examination. The average age of the patients was 6.86±5.09 years. The clinical symptoms, duration of each of the identified symptoms, and complications were evaluated. Acomparative analysis of possible risk factors for prolonged course and development of pneumonia was carried out. Results. The most common cases in children with COVID-19 were an increase in body temperature (in93%), runny nose (in65%), cough (in59%), hyperemia of the posterior pharyngeal wall (in95%) and tonsils (in93%), an increase in regional lymph nodes - in 43%. Among children with the duration of COVID-19 for 10 days or more, astatistically significant late request for medical help (onaverage, by 8.26±5.46 days, compared with 3.00 ± 1.32 days with the duration of the disease up to 10 days). Pneumonia is most often registered among preschool children. The average age in the group of children diagnosed with pneumonia is significantly less than in children who did not have signs of pneumonia of this complication (4.66 ±4.78 and 7.17±4.81, respectively). Conclusions: With the spread of the Omicron variant COVID-19 in children, infection with the SARS-CoV-2 coronavirus is accompanied by symptoms of acute respiratory infection with an increase in body temperature, sore throat, hyperemia of the posterior wall of the pharynx and tonsils. Often there is an increase in regional lymph nodes, runny nose, cough, vomiting, less often - diarrhea. The prolonged course is facilitated by the late onset of adequate therapy. During the study, pneumonia was detected in 25% of children.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Features of clinical picture of pneumonia caused by SARS-COV-2 virus in children

Cited by 2 publications

References 10 publications

Assessment of hematological parameters in children with COVID-19 in the Republic of Sakha (Yakutia)

Assessment of hematological parameters in children with COVID-19 in the Republic of Sakha (Yakutia)

Features of the course of COVID-19 in children with the spread of the Omicron variant

Contact Info

Product

Resources

About