Features of Distribution of Vicia Sativa Agglutinin (Vsa) Receptors in the Intercellular Matrix of the Menisci of Rat Knee Joint After Intrafetal Injection of Antigens

Abstract

FEATURES OF DISTRIBUTION OF VICIA SATIVA AGGLUTININ (VSA) RECEPTORS IN THE INTERCELLULAR MATRIX OF THE MENISCI OF RAT KNEE JOINT AFTER INTRAFETAL INJECTION OF ANTIGENS

Features of Distribution of Soybean Agglutinin (Sba) Receptors in the Extracellular Matrix of the Menisci of Rat Knee Joint After Intrafetal Injection of Antigens

“…Lectins and their receptors provide extracellular, cell-matrix interactions, participate in the regulation of proliferation, differentiation and apoptosis of cells [1,2]. Previously we have shown that distribution of the receptors to other lectins (WGA, VSA) differs in intact knee joint menisci and after intrauterine antigenic effect [4,5].…”

“…One of the effective methods to increase an organism resistance to cerebral ischemia is preconditioning (PreC) [1,2]. Obviously, the role of the glycogen synthase kinase-3β (GSK-3β) pathway is to regulate mitochondrial permeability transition pore (mPTP), a principle trigger of apoptosis and even necrosis [3,4]. The aim of this study was to analyze whether the combined PreC influences the brain GSK-3β level in cerebral ischemia; and compare the data with morphological changes in the most vulnerable to hypoxia CA1 and CA3 hippocampus fields.…”