FEATURES OF DISTRIBUTION OF VICIA SATIVA AGGLUTININ (VSA) RECEPTORS IN THE INTERCELLULAR MATRIX OF THE MENISCI OF RAT KNEE JOINT AFTER INTRAFETAL INJECTION OF ANTIGENS

FEATURES OF DISTRIBUTION OF RECEPTORS TO THE WHEAT GERM AGGLUTININ (WGA) IN THE INTERCELLULAR MATRIX OF THE MENISCI OF RAT KNEE JOINT AFTER INTRAFETAL INJECTION OF ANTIGENS

The present time is characterized by an increase in the pace of life, and medicine is no exception. Often, when analyzing the medical literature, specialists are faced with the fact that in different publications almost the same structure has a different name, which causes misunderstanding among specialists in various medical fields. This is especially true for clinicians who use the convenient anatomical names of fundamental scientists such as morphologists. As these names, terms from the International Anatomical Nomenclature are used, along with which, especially in clinical anatomy and medicine, eponymous names are accepted. The use of the latter can also be misunderstood, because eponyms are absent in modern anatomical terminology. However, additional knowledge of eponyms, along with common terms, gives the opportunity to look into the past and honor the memory of those who first described the structures. The paper attempts to systematize the names - eponyms of human heart structures. The need for such work exists because many structures have several eponymous names. In addition, if you arrange the terms in the chronological order of their occurrence, you can trace the main stages in the history of the human heart study. Despite the large number of eponymous names for the same structure and the doubtful attribution of some authors, the work lists only the most common eponyms in domestic and foreign literature, about the origin and authors of which reliable information was found. In 1955, at the IV International Congress of Anatomists in Paris (Paris Anatomical Nomenclature, PNA), eponymous names were excluded from the terminology. There are a number of objective reasons for this, but at the same time, the main function of eponyms is lost - the preservation and transmission to descendants the memory of major figures of medical science who made a significant contribution to its development. Therefore, despite the exclusion of eponyms from the official terminology, these terms are widely used today both at the departments of universities in the world, and in clinical literature and practice.

Запорізький державний медичний університет Ключові слова: меніск, колінний суглоб, щури, внутрішньоплідне введення антигену, недиференційована дисплазія сполучної тканини.

Background. In Ukraine, there has recently been an increase in the number of limb bone fractures among the population, in particular, due to increase in the number of elderly people, which is associated with the development of age-related osteoporosis and fragility of bones. Therefore, the use of artificial implants in traumatology is becoming increasingly important. The search for new bioinert and biodegradable materials, that are capable of providing rapid fracture consolidation and do not require repeated surgical intervention, continues. Objective. To elaborate a model for the research of using carbon-carbon composite nail for intramedullary osteosynthesis in laboratory rats with fractures of femur and tibia in norm and with experimental osteoporosis. Methods. The work investigated the lower limbs of 6 groups of Wistar rats. The first part of the study involved 4 groups of rats with modeled tibial fracture with subsequent osteosynthesis in norm and with experimental osteoporosis. The second part of the research included two groups of laboratory rats with modeled femur fracture. In both parts we used metal injection needle, as well as carbon-carbon composite nail for osteosynthesis. Results. All animals underwent surgery well, stepped on the injured limb. X-ray examination after the osteosynthesis demonstrated satisfactory reposition of the fragments. One month after modeled fracture in rats with experimental osteoporosis a violation of the normal consolidation of the fracture was observed, especially in the group where carbon-carbon composite nails were used for osteosynthesis. Further, until the 180th day after the surgery there were no peculiarities, function of the limbs was restored, mainly without expressed angular deformities. Conclusion. The above mentioned model was successfully elaborated for the research of using carbon-carbon composite nail for intramedullary osteosynthesis in laboratory rats with fractures of femur and tibia in norm and with experimental osteoporosis.