Researchers have recently focused on new and original roadside barriers that prioritize aesthetic, and environmental concerns by employing natural materials. In this study, the safety performance (Acceleration Severity Index (ASI), Theorical Head Impact Velocity (THIV)), structural performance (Working Width (W), Exit Angle (α)), and failure analysis (visual deformation) of a newly developed Renewable Hybrid Barrier (RHB) system at different timber thicknesses were tried to be determined by pendulum crash test and Finite Element (FE) models. The FE models were calibrated and validated based on pendulum crash test results, and then the most suitable timber thickness in terms of safety and structural performance was determined via FE analyses. The results revealed that as the timber thickness decreased, the safety parameters, such as ASI and THIV, decreased, thus the barrier safety increased. However, it was observed that the deflection and deformations in the barrier increased as the timber thickness decreased. In this sense, the safest and the most structurally durable barrier was determined through conducting virtual optimization tests. Studies on diversification of the usage areas of natural/renewable materials should be increased in the future.