Female pelvic bone marrow: serial MR imaging before, during, and after radiation therapy.

Blomlie, V.; Rofstad, Einar K.; Skjønsberg, Ane; Tverå, K.; Lien, H. H.

doi:10.1148/radiology.194.2.7824737

Cited by 83 publications

(62 citation statements)

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“…In the acute phase, cellular depletion, marrow edema, vascular congestion, and hemorrhage ensue during the first hours and days. Within 1-2 weeks, the observed increase in MR signal intensity in T2-weighted and STIR images is thought to represent a reduction in cellularity and an increase in fat and marrow edema [22,24]. An increase in MR signal on STIR images can be observed as early as 8 days after initiation of RT [22].…”

Section: Post-treatment Changesmentioning

confidence: 99%

“…7) [22]. In the spine, a band pattern of peripheral, intermediate T1 signal intensity has also been noted, and is thought to represent red marrow surrounding a central fatty deposit [24].…”

Section: Post-treatment Changesmentioning

confidence: 99%

“…c Axial contrast-enhanced fat-suppressed T1-weighted MR image reveals mild enhancement of the rim (halo) around the lesion (arrows). d Lesion is sclerotic on CT (arrow), and could have been misdiagnosed as a bone island Changes in marrow signal due to radiation therapy On both MRI and histopathologic evaluation, acute and chronic changes induced by radiation treatment (RT) have been well described [21][22][23][24]. In the acute phase, cellular depletion, marrow edema, vascular congestion, and hemorrhage ensue during the first hours and days.…”

Section: Post-treatment Changesmentioning

confidence: 99%

“…Although lesser and smaller, changes in MR signal are also observed in bone marrow located outside the radiation portal of the spine; the etiology of such changes remains unclear [22,25]. Contrast enhancement of marrow both inside and outside the radiation portal decreases significantly with time; it has been speculated that this decrease in enhancement represents reductions in cellularity and vascularity, and an increase in fatty marrow in response to RT [25].…”

Section: Post-treatment Changesmentioning

confidence: 99%

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Magnetic resonance imaging of bone marrow in oncology, Part 2

Hwang

Panicek

2007

Skeletal Radiol

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Magnetic resonance imaging plays an integral role in the detection and characterization of marrow lesions, planning for biopsy or surgery, and post-treatment followup. To evaluate findings in bone marrow on MR imaging, it is essential to understand the normal composition and distribution of bone marrow and the changes in marrow that occur with age, as well as the basis for the MR signals from marrow and the factors that affect those signals; these points have been reviewed and illustrated in part 1 of this two-part article. Part 2 will emphasize the practical application of MR imaging to facilitate differentiation of normal marrow, tumor, and treatment-related marrow changes in oncology patients, and will review complementary MR techniques under development.

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Section: Post-treatment Changesmentioning

confidence: 99%

“…7) [22]. In the spine, a band pattern of peripheral, intermediate T1 signal intensity has also been noted, and is thought to represent red marrow surrounding a central fatty deposit [24].…”

Section: Post-treatment Changesmentioning

confidence: 99%

Section: Post-treatment Changesmentioning

confidence: 99%

Section: Post-treatment Changesmentioning

confidence: 99%

See 2 more Smart Citations

Magnetic resonance imaging of bone marrow in oncology, Part 2

Hwang

Panicek

2007

Skeletal Radiol

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“…Some studies (Romanos et al 2013 ;Blomlie et al 1995 ) have reported that radiation-induced changes with small but measurable fatty conversion may occur outside the irradiation fi eld but the etiology and signifi cance of such changes remain unclear. The bone marrow outside the irradiation fi eld may show similar MRI signal changes compared to bone marrow within the irradiation fi eld but to a much lower degree.…”

Section: Radiation-induced Changes On Normal Bone Marrowmentioning

confidence: 99%

Female Pelvis: Genital Organs

Forstner

Cunha²

2015

Imaging of Complications and Toxicity Following Tumor Therapy

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Medical Radiology-Diagnostic Imaging is a unique series that aims to document the most innovative technologies in all fi elds within diagnostic imaging and interventional radiology, thereby informing the physician in practice of the latest advances in diagnostic imaging and percutaneous imageguided minimally invasive procedures. Th e contents are intended to cover all organs, and all modern imaging techniques and image-guided treatment modalities, with special emphasis on applications in clinical practice. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. Medical Radiology -Radiation Oncology is a unique series that aims to document the most innovative technologies in all fi elds within radiology, thereby informing the physician in practice of the latest advances in diagnostic and treatment techniques. Th e contents range from contemporary statements relating to management for various disease sites to explanations of the newest techniques for tumor identifi cation and of mechanisms for the enhancement of radiation eff ects, with the emphasis on maximizing cure and minimizing complications. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. AbstractA precise knowledge of antineoplastic drugs is an indispensable basis for the care of patients with cancer. The mechanisms of action and resistance, cross-resistance patterns, pharmacodynamics and pharmacokinetics, pharmacological interaction, and last but not least potential adverse effects should be part of this knowledge. As contemporary cancer care requires interdisciplinary and multiprofessional structures, the radiologist is an important a...

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